Results 171 to 180 of about 82,493 (288)

Aromaticity at spike position 456 affects functional immunogenicity of SARS-CoV-2 Omicron variant receptor-binding domain. [PDF]

Signal Transduct Target Ther
Peng D, Chen Z, Fu M, Hong W, Dai M, Zeng H, Lin S, Lei H, Yang J, Shi J, Huang X, Ye C, Qin F, Zhang Y, Hao Y, Wang B, Ren W, Chen L, Liu J, Alu A, Lu Y, Du X, Li J, Shi H, Wei Y, Chen Y, Lu S, He C, Lu G, Wei X.   +29 more
europepmc   +1 more source

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

The pan-African natural products library compounds oleanolic acid, poinsettifolin B, and rhuschalcone III disrupt SARS-CoV-2 spike-host ACE2 interactions and SARS-CoV-2 replication. [PDF]

BMC Pharmacol Toxicol
Tjegbe MJM, Onguéné PA, Bekono BD, Betow JY, Simoben CV, Cassel J, Salvino JM, Montaner LJ, Andrae-Marobela K, Ntie-Kang F, Tietjen I.   +10 more
europepmc   +1 more source

Dreaming conundrum

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Dreaming, a common yet mysterious cognitive phenomenon, is an involuntary process experienced by individuals during sleep. Although the fascination with dreams dates back to ancient times and gained therapeutic significance through psychoanalysis in the early twentieth century, its scientific investigation only gained momentum with the ...
Carlotta Mutti, Francesca Siclari, Ivana Rosenzweig   +2 more
wiley   +1 more source

The Seattle Trauma and Autonomic Related Sleep Symptoms (STARSS) Scale: A Novel Self‐Report Measure of Sleep Disturbances With Nightmares and Autonomic Symptoms Following Trauma

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep disruption is a common hallmark of posttraumatic stress disorder (PTSD), causing significant distress and often persisting after remission of other symptoms. Autonomic dysregulation is commonly comorbid and has been implicated in the underlying pathophysiology of both wake‐ and sleep‐related symptoms following trauma.
Garth E. Terry, Aaron F. Rosser, Katharine J. Liang, Kim L. Hart, Sarah B. Campbell, Murray A. Raskind, Rebecca C. Hendrickson   +6 more
wiley   +1 more source

Route-Dependent Effects of Pre-Existing Anti-Ad5 Immunity on Systemic, Mucosal and Lymph Node B Cell Responses to an Ad5-Vectored Vaccine. [PDF]

Vaccines (Basel)
Zheng W, Xiang J, Guo X, Zhu L, Zhang Z, Hou L.   +5 more
europepmc   +1 more source

Hepatic Steatosis Risk Is Positively Associated With Increased Intestinal Glucose Absorption

Diabetes, Obesity and Metabolism, EarlyView.
Braden D. Rose, Domenico Tricò, Christopher K. Rayner, Tongzhi Wu, Richard L. Young   +4 more
wiley   +1 more source

Attitudes, Strategies and Value Frameworks Guiding Risk Communication in Isolated REM Behaviour Disorder: A Scoping Review of Perspectives From Patients and Healthcare Professionals

Journal of Sleep Research, EarlyView.
ABSTRACT Idiopathic/isolated REM sleep behaviour disorder (iRBD) is widely recognized as a key prodromal condition associated with a high risk of progression to α‐synucleinopathies. Despite this, disclosure of risk related to such early signs of neurodegeneration remains controversial in clinical practice.
Serena Covino, Ana Borovecki, Marko Ćurković, Laura Adelaide Dalla Vecchia, Beatrice De Maria, Clara Gino, Alessandra Grossi, Mario Picozzi, Davide Sattin, on behalf of the DEEPEN iRBD Consortium   +9 more
wiley   +1 more source

Targeting of conserved spike epitopes enables broad antibody neutralisation of diverse bat sarbecoviruses. [PDF]

PLoS Biol
Upadhyay A, Seow J, Alguel Y, Newman J, Thakur N, Hay AL, Tam JCH, Nans A, Orton RJ, Bailey D, Cherepanov P, Doores KJ.   +11 more
europepmc   +1 more source

A Call to Action: Challenges and Future Directions for Sleep Health in Europe

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep is fundamental to physical, cognitive, and emotional health and wellbeing. However, it is increasingly threatened by environmental, social, technological, and cultural pressures. To identify key priorities for improving sleep health across Europe, the European Sleep Research Society (ESRS)'s Equality, Diversity and Inclusion Committee ...
Fran Pilkington‐Cheney, Claire André, Seren Ucak, Raoua Ben Messaoud, Anna M. Biller, Inês Dias, Jose Prius Mengual, Daniela Noain, Michaela Pawley, Monisha Ravikumar, Matias Rusanen, Laura Stankeviciute, Adriana Michalak   +12 more
wiley   +1 more source