NAT10/ac<sup>4</sup>C drives intrahepatic cholangiocarcinoma by suppressing transposable elements via chromatin remodeling. [PDF]
Lu Y +13 more
europepmc +1 more source
Food consumption and eating disorders in Latin America and the Caribbean: a scoping review. [PDF]
Lozada-Urbano M +3 more
europepmc +1 more source
Quantitative analysis of robustness-based versus LET-based optimization in intensity-modulated proton therapy for pediatric brain tumors. [PDF]
Torsha FK +5 more
europepmc +1 more source
W C, Roesch, W A, Glass
openaire +1 more source
RBE, reference RBE and clinical RBE: Applications of these concepts in hadron therapy [PDF]
Introduction of heavy particles (hadrons) into radiation therapy aims at improving the physical selectivity of the irradiation (e.g. proton beams), or the radiobiological differential effect (e.g. fast neutrons), or both (e.g. heavy-ion beams). Each of these new therapy modalities requires several types of information before prescribing safely the ...
A Wambersie, André Wambersie
exaly +4 more sources
Impact of variable RBE on proton fractionation [PDF]
Purpose:To explore the impact of variable proton relative biological effectiveness (RBE) on dose fractionation for clinically relevant situations. A generic RBE = 1.1 is generally used for isoeffect calculations, while experimental studies showed that proton RBE varies with tissue type, dose, and linear energy transfer (LET).Methods:An analytical ...
Alexandru, Dasu, Iuliana, Toma-Dasu
openaire +3 more sources
RBE of ion beams in hypofractionated radiotherapy (SBRT) [PDF]
An important advantage for the application of carbon ion beams in tumour therapy is their increased relative biological effectiveness (RBE) as compared to conventional photon radiation. Since RBE among other factors depends on the dose level, the precise
Marco Durante +2 more
exaly +2 more sources
An ion-independent phenomenological relative biological effectiveness (RBE) model for proton therapy [PDF]
Background: A relative biological effectiveness (RBE) of 1.1 is used for proton therapy though clinical evidence of varying RBE was raised. Clinical studies on RBE variability have been conducted for decades for carbon radiation, which could advance the ...
Armin Lühr
exaly +2 more sources
Dose prescription in carbon ion radiotherapy: How to compare two different RBE-weighted dose calculation systems [PDF]
Background and purpose: In carbon ion radiotherapy (CIRT), the use of different relative biological effectiveness (RBE) models in the RBE-weighted dose $(D_{RBE})$ calculation can lead to deviations in the physical dose $(D_{phy})$ delivered to the ...
Edoardo Mastella +2 more
exaly +2 more sources

