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Radiotherapy and Oncology, 2016 Background and purpose: In carbon ion radiotherapy (CIRT), the use of different relative biological effectiveness (RBE) models in the RBE-weighted dose $(D_{RBE})$ calculation can lead to deviations in the physical dose $(D_{phy})$ delivered to the ...
Edoardo Mastella +2 more
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RBE of Ion Beams in Hypofractionated Radiotherapy (SBRT)
Physica Medica, 2014 An important advantage for the application of carbon ion beams in tumour therapy is their increased relative biological effectiveness (RBE) as compared to conventional photon radiation. Since RBE among other factors depends on the dose level, the precise
Marco Durante +2 more
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A Systematic Review of Clinical Studies on Variable Proton Relative Biological Effectiveness (RBE)
Radiotherapy and Oncology, 2022 Recently, a number of clinical studies have explored links between possible Relative Biological Effectiveness (RBE) elevations and patient toxicities and/or image changes following proton therapy.
Joanne Haviland +2 more
exaly +2 more sources
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Proceedings of the Eleventh International Conference on Data Engineering, 2002
Rendering is defined to be a customized presentation of data in such a way that allows users to subsequently interact with the presented data. Traditionally such a user interface would be a custom application written using conventional programming languages; in contrast we propose an application-independent, declarative (i.e., what-you-want) language ...
Ravi Krishnamurthy, Moshé M. Zloof
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Rendering is defined to be a customized presentation of data in such a way that allows users to subsequently interact with the presented data. Traditionally such a user interface would be a custom application written using conventional programming languages; in contrast we propose an application-independent, declarative (i.e., what-you-want) language ...
Ravi Krishnamurthy, Moshé M. Zloof
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Nanodosimetry and RBE values in radiotherapy
Radiation Protection Dosimetry, 2015In a recent paper, the authors reported that the dose mean lineal energy, [Formula: see text] in a volume of about 10-15 nm is approximately proportional to the α-parameter in the linear-quadratic relation used in fractionated radiotherapy in both low- and high-LET beams. This was concluded after analyses of reported radiation weighting factors, WisoE (
Lennart, Lindborg +3 more
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Dependence of RBE on neutron dose
The British Journal of Radiology, 1972In a recent article (Alper, 1972) Dr. Alper states that the relative biological effectiveness, R, of neutrons at high neutron doses, DN, varies as the inverse of DN, provided the dose effect curves are exponential at higher doses. This might be considered to be in contradiction to our finding (Rossi, 1970; Kellerer and Rossi, 1971) that over a wide ...
A M, Kellerer, H H, Rossi
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Strahlentherapie und Onkologie, 1999
Beams of heavy ions like carbon offer both, an improved dose distribution superior to any other type of radiation and an increased relative biological efficiency, RBE, which is restricted to the target volume only. The various dependencies of RBE on dose, atomic number and tissue sensitivity are described in this paper and are discussed in the ...
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Beams of heavy ions like carbon offer both, an improved dose distribution superior to any other type of radiation and an increased relative biological efficiency, RBE, which is restricted to the target volume only. The various dependencies of RBE on dose, atomic number and tissue sensitivity are described in this paper and are discussed in the ...
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The RBE of megavoltage photon and electron beams
The British Journal of Radiology, 1978A recent MRC Working Party (1975) was convened to discuss the relative benefits of electron or photon megavoltage beams for therapy. The discussion arose due to a feeling among many radiotherapists that normal tissues (especially skin) would tolerate higher doses from electron beams (up to 20%) than from photon beams of similar primary energy.
P C, Williams, J H, Hendry
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International Journal of Radiation Oncology*Biology*Physics, 1982
The sparing effect of fractionation of neutron dose is very small for late damage in tissues. This is seen in the almost flat isoeffect curve for damage to skin, CNS and to lung. This means that differences in the RBE curves for these tissues are determined by differences in the slopes of the photon isoeffect curves.
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The sparing effect of fractionation of neutron dose is very small for late damage in tissues. This is seen in the almost flat isoeffect curve for damage to skin, CNS and to lung. This means that differences in the RBE curves for these tissues are determined by differences in the slopes of the photon isoeffect curves.
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RBE: Mechanisms inferred from cytogenetics
Advances in Space Research, 1994Cyclotron-accelerated heavy ion beams provide a fine degree of control over the physical parameters of radiation. Cytogenetics affords a view into the irradiated cell at the resolution of chromosomes. Combined they form a powerful means to probe the mechanisms of RBE.
E H, Goodwin, M N, Cornforth
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