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Clinical Evaluation of RBE

1965
Early animal work with the 15MeV linear accelerator at St. Bartholomew’s Hospital indicated that the R.B.E. for electrons compared to 250 kV X-rays was 0.86. This figure was obtained by measuring the L.D.50 for mice subjected to whole-body irradiation.
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Biophysical Models and RBE

2013
A primary goal for treatment delivery is to achieve a homogenous effect throughout the target volume. In contrast to conventional photon therapy, this cannot be achieved by applying a uniform distribution of absorbed dose within the target volume due to the drastic change in the biological effectiveness of ion beam as shown in the previous section.
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RBE in Normal Tissue Studies

1992
Single dose RBEs for the radiations encountered in BNCT have been determined1 and can provide useful guidance for the tolerance to be expected. The difficulty of microdosimetric determination of dose2, the rapidly varying mix of constituent high and low LET radiations with depth, the possible synergistic interaction between high and low LET radiations3,
Reinhard A. Gahbauer   +3 more
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Chromosome Aberrations and the Theory of RBE

International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1965
SummaryIt is suggested that primary radiation damage to a macromolecule in a cell which may lead to observable biological effect is normally the direct effect of a single energy-loss event in the macromolecule. This concept is applied to the production of chromosome aberrations, regarding a local region of a chromosome as a molecule of DNA, and ...
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The RBE in ion beam radiotherapy: In vivo studies and clinical application

Zeitschrift Fur Medizinische Physik, 2021
Christin Glowa   +2 more
exaly  

RBE Modifying Factors

Radiation Protection Dosimetry, 1992
M. Coppola   +3 more
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Dose-rate, rbe, and oer.

Strahlentherapie, 1981
An analysis of the theories and experimental data dealing with dose-rate effect, relative biological effectiveness (rbe), and oxygen enhancement ratio (oer) for mammalian cells, indicate that neither the theories nor the experimental data themselves are helpful in establishing general rules regarding variations of rbe or oer with dose-rate.
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