Results 51 to 60 of about 130,598 (99)

Current and future treatments for Alzheimer’s disease

open access: yesTherapeutic Advances in Neurological Disorders, 2013
Alzheimer’s dementia (AD) is increasingly being recognized as one of the most important medical and social problems in older people in industrialized and non-industrialized nations.
Konstantina G. Yiannopoulou   +1 more
doaj   +1 more source

The feasibility, reliability and concurrent validity of the MSReactor computerized cognitive screening tool in multiple sclerosis

open access: yesTherapeutic Advances in Neurological Disorders, 2019
Background: Multiple sclerosis (MS) cognitive tests are resource intensive and limited by practice effects that prevent frequent retesting. Brief, reliable and valid monitoring tools are urgently needed to detect subtle, subclinical cognitive changes in ...
Daniel Merlo   +4 more
doaj   +1 more source

The Role of Onabotulinum Toxin Type A in the Management of Chronic Non-migraine Headaches

open access: yesFrontiers in Neurology, 2019
Objectives: FDA has approved Onabotulinum toxin type A (BoNTA) for prophylactic treatment of chronic migraines. Recent studies have explored its potential new indications, like treating post-traumatic headaches.Patients and Methods: This is a ...
Cassie Jia   +3 more
doaj   +1 more source

miR-200b/200a/429 Cluster Stimulates Ovarian Cancer Development by Targeting ING5

open access: yesJournal of Oncology, 2020
Ovarian cancer is the second most common gynaecological malignancy, and microRNAs (miRNAs) play important role in the cancer development. Here, we found that the level of miR-200b/200a/429 was significantly increased in serum and tumor tissues of ...
W. Guan   +6 more
semanticscholar   +1 more source

Inflammation in stroke: the role of cholinergic, purinergic and glutamatergic signaling

open access: yesTherapeutic Advances in Neurological Disorders, 2018
The inflammatory response is a major factor in stroke pathophysiology and contributes to secondary neuronal damage in both acute and chronic stages of the ischemic injury.
Abraham Martín   +2 more
doaj   +1 more source

A peripheral neutrophil-related inflammatory factor predicts a decline in executive function in mild Alzheimer’s disease

open access: yesJournal of Neuroinflammation, 2020
Background Studies suggest a role of the innate immune system, including the activity of neutrophils, in neurodegeneration related to Alzheimer’s disease (AD), but prospective cognitive data remain lacking in humans.
Kritleen K. Bawa   +10 more
doaj   +1 more source

miR-429-3p/LPIN1 Axis Promotes Chicken Abdominal Fat Deposition via PPARγ Pathway

open access: yesFrontiers in Cell and Developmental Biology, 2020
To explore the regulatory mechanism of abdominal fat deposition in broilers, 100-day-old Sanhuang chickens (n = 12) were divided into high-fat and low-fat groups, according to the abdominal fat ratio size.
Xiaohuan Chao   +11 more
semanticscholar   +1 more source

Differential functioning of mini-mental test items according to disease

open access: yesNeurología (English Edition), 2011
Introduction: Comparing the height of males and females would be impossible if the measuring device did not have the same properties for both populations.
G. Prieto   +3 more
doaj   +1 more source

NFATc2-dependent epigenetic upregulation of CXCL14 is involved in the development of neuropathic pain induced by paclitaxel

open access: yesJournal of Neuroinflammation, 2020
Background The major dose-limiting toxicity of paclitaxel, one of the most commonly used drugs to treat solid tumor, is painful neuropathy. However, the molecular mechanisms underlying paclitaxel-induced painful neuropathy are largely unclarified ...
Meng Liu   +11 more
doaj   +1 more source

Transportation Time is Significantly Decreased in Acute Ischemic Stroke Patients Under Drip-and-Ship Paradigm for Thrombolysis [PDF]

open access: yesJournal of Neurocritical Care, 2018
Background A delay of transfer for patients with acute stroke needing emergent revascularization is a huge hurdle for efficacy of revascularization. The objective of this study was to investigate changes of transportation time calculated by image to door
Jeong-Yeon Kim   +4 more
doaj   +1 more source

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