Results 1 to 10 of about 96,018 (50)

Optimization of In vivo Imaging Provides a First Look at Mouse Model of Non-Alcoholic Fatty Liver Disease (NAFLD) Using Intravital Microscopy

Frontiers in Immunology, 2020
Non-alcoholic fatty liver disease is a spectrum of liver pathology ranging from simple steatosis to steatohepatitis and can progress to diseases associated with poor outcomes including cirrhosis and hepatocellular carcinoma (HCC).
Rachelle P. Davis, Rachelle P. Davis, Bas G. J. Surewaard, Bas G. J. Surewaard, Bas G. J. Surewaard, Madison Turk, Madison Turk, Agostina Carestia, Agostina Carestia, Woo-Yong Lee, Woo-Yong Lee, Björn Petri, Björn Petri, Stefan J. Urbanski, Carla S. Coffin, Carla S. Coffin, Craig N. Jenne, Craig N. Jenne   +17 more
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Assessment of Immunological Response and Impacts on Fertility Following Intrauterine Vaccination Delivered to Swine in an Artificial Insemination Dose

Frontiers in Immunology, 2020
To protect the health of sows and gilts, significant investments are directed toward the development of vaccines against infectious agents that impact reproduction.
Glenn Hamonic, Glenn Hamonic, J. Alex Pasternak, Siew Hon Ng, Kezia R. Fourie, Olena M. Simko, Brodie Deluco, Heather L. Wilson, Heather L. Wilson   +8 more
doaj   +1 more source

Mass Cytometry Analysis Reveals Complex Cell-State Modifications of Blood Myeloid Cells During HIV Infection

Frontiers in Immunology, 2019
Dendritic cells (DC), which are involved in orchestrating early immune responses against pathogens, are dysregulated in their function by HIV infection. This dysregulation likely contributes to tip the balance toward viral persistence.
Sixtine Coindre, Nicolas Tchitchek, Lamine Alaoui, Bruno Vaslin, Christine Bourgeois, Cecile Goujard, Cecile Goujard, Camille Lecuroux, Pierre Bruhns, Roger Le Grand, Anne-Sophie Beignon, Olivier Lambotte, Olivier Lambotte, Benoit Favier   +13 more
doaj   +1 more source

Circulating Plasmablasts from Chronically Human Immunodeficiency Virus-Infected Individuals Predominantly Produce Polyreactive/Autoreactive Antibodies

Frontiers in Immunology, 2017
Understanding the B-cell response during chronic human immunodeficiency virus (HIV) infection is essential for eliciting broad and potent neutralizing antibodies (Abs).
Hongyan Liao, Hongyan Liao, Yangsheng Yu, Song Li, Song Li, Yinshi Yue, Chuanmin Tao, Kaihong Su, Kaihong Su, Kaihong Su, Zhixin Zhang, Zhixin Zhang   +11 more
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Dynamics of Colon Monocyte and Macrophage Activation During Colitis

Frontiers in Immunology, 2018
Background: Macrophages are pivotal in coordinating a range of important processes in the intestines, including controlling intracellular infections and limiting damaging inflammation against the microbiota.
Gareth-Rhys Jones, Gareth-Rhys Jones, Calum C. Bain, Thomas M. Fenton, Aoife Kelly, Aoife Kelly, Sheila L. Brown, Alasdair C. Ivens, Mark A. Travis, Mark A. Travis, Peter C. Cook, Andrew S. MacDonald   +11 more
doaj   +1 more source

Insight into the Endocrine System and the Immune System: A Review of the Inflammatory Role of Prolactin in Rheumatoid Arthritis and Psoriatic Arthritis

Frontiers in Immunology, 2017
Rheumatoid arthritis (RA) is a chronic autoimmune disease that affects females three times more frequently than males. A potential role for hormones, such as prolactin (PRL), may in part explain this phenomenon.
Man W. Tang, Man W. Tang, Samuel Garcia, Danielle M. Gerlag, Danielle M. Gerlag, Paul P. Tak, Paul P. Tak, Paul P. Tak, Paul P. Tak, Kris A. Reedquist   +9 more
doaj   +1 more source

Systemic β-Adrenergic Receptor Activation Augments the ex vivo Expansion and Anti-Tumor Activity of Vγ9Vδ2 T-Cells

Frontiers in Immunology, 2020
TCR-gamma delta (γδ) T-cells are considered important players in the graft-vs.-tumor effect following allogeneic hematopoietic cell transplantation (alloHCT) and have emerged as candidates for adoptive transfer immunotherapy in the treatment of both ...
Forrest L. Baker, Forrest L. Baker, Forrest L. Baker, Austin B. Bigley, Nadia H. Agha, Charles R. Pedlar, Daniel P. O'Connor, Richard A. Bond, Catherine M. Bollard, Emmanuel Katsanis, Emmanuel Katsanis, Richard J. Simpson, Richard J. Simpson, Richard J. Simpson, Richard J. Simpson   +14 more
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Immunization With a DNA Vaccine Cocktail Encoding TgPF, TgROP16, TgROP18, TgMIC6, and TgCDPK3 Genes Protects Mice Against Chronic Toxoplasmosis

Frontiers in Immunology, 2018
Toxoplasmosis is a zoonotic disease caused by the intracellular protozoan Toxoplasma gondii; and a major source of infection in humans is via ingestion of T. gondii tissue cysts.
Nian-Zhang Zhang, Qi Gao, Qi Gao, Meng Wang, Hany M. Elsheikha, Bo Wang, Jin-Lei Wang, Fu-Kai Zhang, Ling-Ying Hu, Xing-Quan Zhu, Xing-Quan Zhu   +10 more
doaj   +1 more source

Resolvin E1 Promotes Bone Preservation Under Inflammatory Conditions

Frontiers in Immunology, 2018
Resolvins are endogenous lipid mediators derived from omega-3 fatty acids. Resolvin E1 (RvE1), derived from eicosapentaenoic acid (EPA), modulates osteoclasts and immune cells in periodontal disease models.
Karim El Kholy, Karim El Kholy, Karim El Kholy, Karim El Kholy, Marcelo Freire, Tsute Chen, Thomas E. Van Dyke, Thomas E. Van Dyke   +7 more
doaj   +1 more source

Obesity-Associated Alterations of Natural Killer Cells and Immunosurveillance of Cancer

Frontiers in Immunology, 2020
Obesity is accompanied by a systemic chronic low-grade inflammation as well as dysfunctions of several innate and adaptive immune cells. Recent findings emphasize an impaired functionality and phenotype of natural killer (NK) cells under obese conditions.
Ina Bähr, Julia Spielmann, Dagmar Quandt, Dagmar Quandt, Heike Kielstein   +4 more
doaj   +1 more source