Results 11 to 20 of about 123,088 (97)
Background Triple negative breast cancer (TNBC) is a major subtype of breast cancer, with limited therapeutic drugs in clinical. Epidermal growth factor receptor (EGFR) is reported to be overexpressed in various TNBC cells.
Tianfeng Yang +8 more
semanticscholar +1 more source
Type 2 diabetes mellitus (T2DM) is a multifactorial disorder that leads to alterations in gene regulation. ncRNAs have the characteristics of tissue specificity, disease specificity, timing specificity, high stability and post transcriptional regulation ...
Manna Su +6 more
semanticscholar +1 more source
Context Differences of sex development (DSD) represent a wide range of conditions presenting at different ages to various health professionals. Establishing a diagnosis, supporting the family, and developing a management plan are important.
E. Man +25 more
semanticscholar +1 more source
Background: Circular RNAs (CircRNAs) have attracted a growing interest of research in cancer. The regulatory roles and mechanisms of circRNAs in progression, metastasis and drug resistance of esophageal squamous cell carcinoma (ESCC) needed to be ...
Yuming Wang +9 more
semanticscholar +1 more source
Emerging evidence has demonstrated that circular RNAs (circRNAs) are abnormally expressed in non-small cell lung carcinoma (NSCLC). However, the contributions of circRNAs to the tumorigenesis of lung adenocarcinoma (LUAD), one of the subtypes of NSCLC ...
W. Mo +5 more
semanticscholar +1 more source
Mast Cells Drive Systemic Inflammation and Compromised Bone Repair After Trauma
There is evidence that mast cells contribute to inflammation induced by hemorrhagic shock, severe tissue injury or sepsis. Mast cells are highly responsive to alarm signals generated after trauma, and release many inflammatory mediators including ...
Deniz Ragipoglu +7 more
doaj +1 more source
Phosphatidylcholine mediates the crosstalk between LET-607 and DAF-16 stress response pathways
Coordinated regulation of stress response pathways is crucial for cellular homeostasis. However, crosstalk between the different stress pathways and the physiological significance of this crosstalk remain poorly understood. In this study, using the model
Bin Z. He +3 more
semanticscholar +1 more source
Osteosarcoma (OS), a type of malignant bone tumor, is commonly found in children and adolescents. Although previous studies have identified that long non-coding RNAs (lncRNAs) regulate OS, it is unclear whether lncRNAs impact the progression of OS. Here,
Yuehuan Zheng +4 more
semanticscholar +1 more source
Background. One of the microRNAs (miRNAs) known to be associated with cancer development is miR‐607. The aim of this study is to investigate the clinical significance and diagnostic and prognostic value of miR‐607 and to explore its potential role in ...
Dawei Jiang +5 more
semanticscholar +1 more source
Background The development of pretreatment drug resistance (PDR) is becoming an obstacle to the success of antiretroviral therapy (ART). Besides, data from developing settings including Ethiopia is still limited. Therefore, this study was aimed to assess
Mulugeta Kiros +6 more
doaj +1 more source

