Results 11 to 20 of about 96,018 (50)
Secretory IgA (SIgA): designed for antimicrobial defence
Frontiers in Immunology, 2013 Prevention of infections by vaccination remains a compelling goal to improve public health. Mucosal vaccines would make immunization procedures easier, be better suited for mass administration, and most efficiently induce immune exclusion -- a term ...
Per eBrandtzaeg
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The Delay in the Licensing of Protozoal Vaccines: A Comparative History
Frontiers in Immunology, 2020 Although viruses and bacteria have been known as agents of diseases since 1546, 250 years went by until the first vaccines against these pathogens were developed (1796 and 1800s).
Clarisa Beatriz Palatnik-de-Sousa +2 more
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Tertiary Lymphoid Structures: Autoimmunity Goes Local
Frontiers in Immunology, 2018 Tertiary lymphoid structures (TLS) are frequently observed in target organs of autoimmune diseases. TLS present features of secondary lymphoid organs such as segregated T and B cell zones, presence of follicular dendritic cell networks, high endothelial ...
Elena Pipi +6 more
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Unraveling Natural Killer T-Cells Development
Frontiers in Immunology, 2018 Natural killer T-cells are a subset of innate-like T-cells with the ability to bridge innate and adaptive immunity. There is great interest in harnessing these cells to improve tumor therapy; however, greater understanding of invariant NKT (iNKT) cell ...
Sabrina Bianca Bennstein
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Frontiers in Immunology, 2016 Upon infection with intracellular bacteria, nucleotide oligomerization domain protein 2 (NOD2) recognizes bacterial muramyl dipeptide and binds, subsequently, to receptor-interacting serine/threonine kinase 2 (RIPK2).
Katharina eWex +9 more
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ASCT2 (SLC1A5)-Deficient Mice Have Normal B-Cell Development, Proliferation, and Antibody Production
Frontiers in Immunology, 2017 SLC1A5 (solute carrier family 1, member 5) is a small neutral amino acid exchanger that is upregulated in rapidly proliferating lymphocytes but also in many primary human cancers. Furthermore, cancer cell lines have been shown to require SLC1A5 for their
Etienne Masle-Farquhar +5 more
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Vaccine Strategies to Improve Anti-cancer Cellular Immune Responses
Frontiers in Immunology, 2019 More than many other fields in medicine, cancer vaccine development has been plagued by a wide gap between the massive amounts of highly encouraging preclinical data on one hand, and the disappointing clinical results on the other.
Karim Vermaelen
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Innate immune complexity in the purple sea urchin: diversity of the Sp185/333 system
Frontiers in Immunology, 2012 The California purple sea urchin, Strongylocentrotus purpuratus, is a long-lived echinoderm with a complex and sophisticated innate immune system. Several large gene families that function in immunity in this species includes the Sp185/333 gene family ...
L. Courtney Smith
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IL-9 Deficiency Promotes Pulmonary Th17 Response in Murine Model of Pneumocystis Infection
Frontiers in Immunology, 2018 IntroductionPneumocystis pneumonia (PCP) remains a severe complication with high mortality in immunocompromised patients. It has been well accepted that CD4+ T cells play a major role in controlling Pneumocystis infection.
Ting Li +4 more
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Serum levels of periostin and exercise-induced bronchoconstriction in asthmatic children
World Allergy Organization Journal, 2019 Background: Periostin is induced by IL-13 and has been studied as a biomarker of asthma. The present study explored the relationship between serum levels of periostin and exercise-induced bronchoconstriction (EIB) in asthmatic children.
Ju Hwan Cho +8 more
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