Results 11 to 20 of about 123,088 (97)

Cantharidin induces apoptosis of human triple negative breast cancer cells through mir-607-mediated downregulation of EGFR

Journal of Translational Medicine, 2023
Background Triple negative breast cancer (TNBC) is a major subtype of breast cancer, with limited therapeutic drugs in clinical. Epidermal growth factor receptor (EGFR) is reported to be overexpressed in various TNBC cells.
Tianfeng Yang, Runze Yu, Cheng Cheng, Jian Huo, Zhengyan Gong, Hanbing Cao, Yu Hu, B. Dai, Yanmin Zhang   +8 more
semanticscholar   +1 more source

hsa-miR-607, lncRNA TUG1 and hsa_circ_0071106 can be combined as biomarkers in type 2 diabetes mellitus

Experimental biology and medicine, 2022
Type 2 diabetes mellitus (T2DM) is a multifactorial disorder that leads to alterations in gene regulation. ncRNAs have the characteristics of tissue specificity, disease specificity, timing specificity, high stability and post transcriptional regulation ...
Manna Su, Tongxin Yu, Yongji Yu, Q. Cheng, Ying-feng Zheng, Rifang Liao, Zhuanping Zeng   +6 more
semanticscholar   +1 more source

A Single-Center, Observational Study of 607 Children and Young People Presenting With Differences of Sex Development (DSD)

Journal of the Endocrine Society, 2022
Context Differences of sex development (DSD) represent a wide range of conditions presenting at different ages to various health professionals. Establishing a diagnosis, supporting the family, and developing a management plan are important.
E. Man, I. Mushtaq, A. Barnicoat, P. Carmichael, C. Hughes, K. Davies, H. Aitkenhead, R. Amin, C. Buchanan, A. Cherian, N. Costa, S. Creighton, P. Duffy, E. Hewson, P. Hindmarsh, Louisa C Monzani, Catherine Peters, P. Ransley, N. Smeulders, H. Spoudeas, D. Wood, I. Hughes, H. Katugampola, C. Brain, M. Dattani, J. Achermann   +25 more
semanticscholar   +1 more source

Circular RNA hsa_circ_0003823 promotes the Tumor Progression, Metastasis and Apatinib Resistance of Esophageal Squamous Cell Carcinoma by miR-607/CRISP3 Axis

International Journal on Biological Sciences, 2022
Background: Circular RNAs (CircRNAs) have attracted a growing interest of research in cancer. The regulatory roles and mechanisms of circRNAs in progression, metastasis and drug resistance of esophageal squamous cell carcinoma (ESCC) needed to be ...
Yuming Wang, Qilong Zhao, Zhi-Yong Sun, Haiping Lin, Xin Xu, M. Cao, Yuchang Fu, Xiaohong Zhao, Xiu-mei Ma, Qing Ye   +9 more
semanticscholar   +1 more source

Circular RNA hsa_circ_0072309 promotes tumorigenesis and invasion by regulating the miR-607/FTO axis in non-small cell lung carcinoma

Aging, 2021
Emerging evidence has demonstrated that circular RNAs (circRNAs) are abnormally expressed in non-small cell lung carcinoma (NSCLC). However, the contributions of circRNAs to the tumorigenesis of lung adenocarcinoma (LUAD), one of the subtypes of NSCLC ...
W. Mo, Liping Deng, Yun-Hsia Cheng, Wenjuan Yu, Yan-hua Yang, W. Gu   +5 more
semanticscholar   +1 more source

Mast Cells Drive Systemic Inflammation and Compromised Bone Repair After Trauma

Frontiers in Immunology, 2022
There is evidence that mast cells contribute to inflammation induced by hemorrhagic shock, severe tissue injury or sepsis. Mast cells are highly responsive to alarm signals generated after trauma, and release many inflammatory mediators including ...
Deniz Ragipoglu, Jasmin Bülow, Kristin Hauff, Martin Voss, Melanie Haffner-Luntzer, Anne Dudeck, Anita Ignatius, Verena Fischer   +7 more
doaj   +1 more source

Phosphatidylcholine mediates the crosstalk between LET-607 and DAF-16 stress response pathways

PLoS Genetics, 2021
Coordinated regulation of stress response pathways is crucial for cellular homeostasis. However, crosstalk between the different stress pathways and the physiological significance of this crosstalk remain poorly understood. In this study, using the model
Bin Z. He, Jie Xu, Shanshan Pang, Haiqing Tang   +3 more
semanticscholar   +1 more source

Silencing of Long Non-Coding RNA LINC00607 Prevents Tumor Proliferation of Osteosarcoma by Acting as a Sponge of miR-607 to Downregulate E2F6

Frontiers in Oncology, 2021
Osteosarcoma (OS), a type of malignant bone tumor, is commonly found in children and adolescents. Although previous studies have identified that long non-coding RNAs (lncRNAs) regulate OS, it is unclear whether lncRNAs impact the progression of OS. Here,
Yuehuan Zheng, Zhe Chen, Zezhu Zhou, Xiang-Yang Xu, Huilin Yang   +4 more
semanticscholar   +1 more source

Low Serum miR-607 Level as a Potential Diagnostic and Prognostic Biomarker in Patients of Pancreatic Ductal Adenocarcinoma: A Preliminary Study

Canadian Journal of Gastroenterology and Hepatology, 2021
Background. One of the microRNAs (miRNAs) known to be associated with cancer development is miR‐607. The aim of this study is to investigate the clinical significance and diagnostic and prognostic value of miR‐607 and to explore its potential role in ...
Dawei Jiang, Xiangfei Yuan, J. Ni, Lan Shen, M. Cai, Liu Xu   +5 more
semanticscholar   +1 more source

Increased HIV-1 pretreatment drug resistance with consistent clade homogeneity among ART-naive HIV-1 infected individuals in Ethiopia

Retrovirology, 2020
Background The development of pretreatment drug resistance (PDR) is becoming an obstacle to the success of antiretroviral therapy (ART). Besides, data from developing settings including Ethiopia is still limited. Therefore, this study was aimed to assess
Mulugeta Kiros, Dawit Hailu Alemayehu, Eleni Geberekidan, Adane Mihret, Melanie Maier, Woldaregay Erku Abegaz, Andargachew Mulu   +6 more
doaj   +1 more source