Results 21 to 30 of about 96,018 (50)

Immunological targets for cancer therapy: new recognition

ImmunoTargets and Therapy, 2018
Michael R Shurin1,21Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA; 2Department of Immunology, University of Pittsburgh Medical Center, Pittsburgh, PA, USADuring the last decade, we have witnessed exhilarating ...
Shurin MR
doaj  

Effect of Genetic Variation of IL-13 on Airway Remodeling in Bronchial Asthma

Allergology International, 2011
Background: IL-13 is a major stimulator of inflammation and tissue remodeling at sites of Th2 inflammation, and common single-nucleotide polymorphisms in IL13 are associated with allergic phenotypes in several ethnically diverse populations.
Hiromi Nagashima, Yutaka Nakamura, Hiroyuki Kanno, Takashi Sawai, Hiroshi Inoue, Kohei Yamauchi   +5 more
doaj   +1 more source

The Differences in the Involvements of Loci of Promoter Region and Ile50Val in Interleukin-4 Receptor α Chain Gene between Atopic Dermatitis and Japanese Cedar Pollinosis

Allergology International, 2012
Background: Atopic dermatitis (AD) and Japanese cedar pollinosis (JCP) are common chronically allergic diseases associated with the activation of T-helper 2 cells. Recent studies have shown that polymorphisms in the genes for IL-4 receptor α chain (IL4RA)
Takeshi Tanaka, Yoshiaki Hitomi, Yasuhiro Kambayashi, Yuri Hibino, Yuma Fukutomi, Aki Shibata, Naotoshi Sugimoto, Kotaro Hatta, Akira Eboshida, Tadashi Konoshita, Hiroyuki Nakamura   +10 more
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Pathogen-Reactive T Helper Cell Analysis in the Pig

Frontiers in Immunology, 2017
There is growing interest in studying host–pathogen interactions in human-relevant large animal models such as the pig. Despite the progress in developing immunological reagents for porcine T cell research, there is an urgent need to directly assess ...
Friederike Ebner, Patrycja Schwiertz, Svenja Steinfelder, Robert Pieper, Jürgen Zentek, Nicole Schütze, Christoph G. Baums, Gottfried Alber, Peter Geldhof, Susanne Hartmann   +9 more
doaj   +1 more source

Effects of maternal inflammation and exposure to cigarette smoke on birth weight and delivery of preterm babies in a cohort of Indigenous Australian women

Frontiers in Immunology, 2015
Sudden Infant Death Syndrome (SIDS), neonatal deaths and deaths from infection are higher among Indigenous Australians. This study aimed to determine the effects of inflammatory responses and exposure to cigarette smoke, two important factors associated ...
Kirsty ePringle, Kirsty ePringle, Kym eRae, Kym eRae, Kym eRae, Loretta eWeatherall, Loretta eWeatherall, Loretta eWeatherall, Sharron eHall, Sharron eHall, Christine eBurns, Christine eBurns, Roger eSmith, Roger eSmith, Eugenie Ruth Lumbers, Eugenie Ruth Lumbers, C. Caroline Blackwell, C. Caroline Blackwell, C. Caroline Blackwell   +18 more
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Epstein-Barr Virus (EBV)-Related Lymphoproliferative Disorders in Ataxia Telangiectasia: Does ATM Regulate EBV Life Cycle?

Frontiers in Immunology, 2019
Epstein-Barr virus (EBV) is an ubiquitous herpesvirus with a tropism for epithelial cells (where lytic replication occurs) and B-cells (where latency is maintained).
Moussab Tatfi, Olivier Hermine, Felipe Suarez   +2 more
doaj   +1 more source

Asymmetry in Erythroid-Myeloid differentiation switch and the role of timing in a binary cell fate decision

Frontiers in Immunology, 2013
GATA1-PU.1 genetic switch is a paradigmatic genetic switch that governs the differentiation of progenitor cells into two different fates, erythroid and myeloid fates.
Afnan eAlagha, Alexey eZaikin
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The More, The Better: “Do the Right Thing” For Natural Killer Immunotherapy in Acute Myeloid Leukemia

Frontiers in Immunology, 2017
Natural killer (NK) cells are circulating CD3− lymphocytes, which express CD56 or CD16 and an array of inhibitory receptors, called killer-immunoglobulin-like receptors (KIRs).
Sarah Parisi, Mariangela Lecciso, Darina Ocadlikova, Valentina Salvestrini, Marilena Ciciarello, Dorian Forte, Giulia Corradi, Michele Cavo, Antonio Curti   +8 more
doaj   +1 more source

Quantitative Methods for Measuring Repair Rates and Innate-Immune Cell Responses in Wounded Mouse Skin

Frontiers in Immunology, 2018
In skin wounds, innate-immune cells clear up tissue debris and microbial contamination, and also secrete cytokines and other growth factors that impact repair process such as re-epithelialization and wound closure.
Zhi Li, Zhi Li, Elizabeth Gothard, Mark C. Coles, Mark C. Coles, Carrie A. Ambler   +5 more
doaj   +1 more source

Effect of Transdermal Tulobuterol Added to Inhaled Corticosteroids in Asthma Patients

Allergology International, 2005
Background: Tulobuterol tape is the first long-acting transdermal preparation of a p2-agonist designed to release tulobuterol in an optimal fashion over a 24-hour period.
Gen Tamura, Yasuyuki Sano, Kazuto Hirata, Shinichi Ishioka, Mitsuyoshi Nakashima, Terumasa Miyamoto   +5 more
doaj   +1 more source