Results 181 to 190 of about 46,334 (221)

Identification and full genome sequencing of previously unknown sandfly-borne phleboviruses using a newly established capture-based next-generation sequencing approach. [PDF]

J Clin Microbiol
Ogola EO, Slothouwer I, Rotich G, Kopp A, Bastos ADS, Getugi C, Melchert J, Jones TC, Omoga DCA, Sang R, Torto B, Tchouassi DP, Junglen S.   +12 more
europepmc   +1 more source

Molecular docking insights of Nigella sativa compounds as potential antiviral inhibitory agents against the replication-machinery proteins VPg and RdRP in rabbit hemorrhagic disease virus (RHDV). [PDF]

Virol J
Afifi YR, El-Akkad TA, Badr OA, Ibrahim SD, Serag AM.   +4 more
europepmc   +1 more source

Antiviral Activity of Ethyl Gallate Against Zika Virus: In Vitro and In Silico Studies. [PDF]

Int J Mol Sci
Lee YJ, Kang N, Heo JH, Kim EA, Heo SJ.
europepmc   +1 more source

Molecular epidemiology and genomic analysis of bulbul coronavirus in Guangdong, China. [PDF]

Front Vet Sci
Zhang L, Chen S, Li H, Li L, Liu H.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

HCV RdRp, sofosbuvir and beyond

2021
The therapeutic targeting of the nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp) of the Hepatitis C Virus (HCV) with nucleotide analogs led to a deep understanding of this enzymes structure, function and substrate specificity. Unlike previously studied DNA polymerases including the reverse transcriptase of Human Immunodeficiency ...
Joy Y, Feng, Adrian S, Ray
openaire   +2 more sources

Cinnamic acid inhibits Zika virus by inhibiting RdRp activity

Antiviral Research, 2021
In recent years, Zika virus (ZIKV), which causes severe diseases such as congenital microcephaly and Guillain-Barré syndrome, bringing serious harm to humans, has spread throughout the world. However, there are currently no effective drugs against the virus, and the need to develop anti-ZIKV drugs is thus urgent.
Yuting Chen, Zhaoxin Li, Pan Pan, Zizhao Lao, Jiangtao Xu, Zonghui Li, Shaofeng Zhan, Xiaohong Liu, Yina Wu, Wenbiao Wang, Geng Li   +10 more
openaire   +2 more sources

Fluorometric RdRp assay with self-priming RNA

Virus Genes, 2015
There is an outmost need for the identification of specific antiviral compounds. Current antivirals lack specificity, making them susceptible to off-target effects, and highlighting importance of development of assays to discover antivirals targeting viral specific proteins.
Fatih, Kocabas, Raife D, Turan, Galip S, Aslan   +2 more
openaire   +2 more sources

Bunyaviridae RdRps: structure, motifs, and RNA synthesis machinery

Critical Reviews in Microbiology, 2017
Bunyaviridae family is the largest and most diverse family of RNA viruses. It has more than 350 members divided into five genera: Orthobunyavirus, Phlebovirus, Nairovirus, Hantavirus, and Tospovirus. They are present in the five continents, causing recurrent epidemics, epizootics, and considerable agricultural loss.
Abdennour Amroun, Stéphane Priet, Xavier de Lamballerie, Gilles Quérat   +3 more
openaire   +2 more sources