Impact of unilateral single-mode balance training vs. combined balance and plyometric training on soccer players' interlimb asymmetry in balance and neuromuscular performance. [PDF]
Muehlbauer T +4 more
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Correction: Dietary behaviors and physical fitness among Chinese adolescents aged 13-16 years: a comparative study on breakfast, eggs, dairy, and sugar-sweetened beverages by urban-rural location and sex. [PDF]
Li Y +6 more
europepmc +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Evaluating headwater hydrology: Tracer dye studies reveal prolonged residence times and potential modeling limitations during severe low-flow periods. [PDF]
Jacobson A, Guth N, Goodwin G, Brain R.
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Deficits in dynamic stability revealed by the Y-Balance test in middle-aged and elderly adults with patellofemoral pain. [PDF]
Zheng Z, Fan H, Hongjie H, Jianquan W.
europepmc +1 more source
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source

