Results 131 to 140 of about 1,600,579 (309)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Understanding the catalytic performance and stability of titania-containing silica catalysts in methyl oleate epoxidation for sustainable biorefinery processes

Journal of King Saud University: Engineering Sciences
Biomass is a renewable and eco-friendly alternative to fossil fuels and can contribute substantially to achieve an efficient industrial symbiosis. Specifically, vegetable oils conversion to biofuels is an attractive alternative to fossil fuels.
Rafik Rajjak Shaikh, Warinya Sukkaew, Supareak Praserthdam, Piyasan Praserthdam   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Electrocatalytic overall water splitting based on (ZnNiCoFeY)xOy high-entropy oxide supported on MoS2

South African Journal of Chemical Engineering
Hydrogen energy is a sustainable and clean source that can meet global energy demands without adverse environmental impacts. High-entropy oxides (HEOs), multielement (5 or more) oxides with an equiatomic or near-equatomic elemental composition, offer a ...
Sumayya C. Pathan, Jasmin S. Shaikh, Navajsharif S. Shaikh, Victor Márquez, Meena Rittiruam, Tinnakorn Saelee, Patcharaporn Khajondetchairit, Sawanta S. Mali, Jyoti V. Patil, Chang Kook Hong, Piyasan Praserthdam, Supareak Praserthdam   +11 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Absence of Photosynthetic Reaction Center Polypeptide H in Rhodopseudomonas sphaeroides

, 1983
An Mr 27,500 membrane protein from Rhodopseudomonas sphaeroides strain 8-17, a non-photosynthetic bacteriochlorophyll-less mutant, has been reported to be the photosynthetic reaction center subunit H found in all photosynthetic isolates of R. sphaeroides.
Gillies, Kevin
core  

Generic Interpretable Reaction Condition Predictions with Open Reaction Condition Datasets and Unsupervised Learning of Reaction Center. [PDF]

Research (Wash D C), 2023
Wang X, Hsieh CY, Yin X, Wang J, Li Y, Deng Y, Jiang D, Wu Z, Du H, Chen H, Li Y, Liu H, Wang Y, Luo P, Hou T, Yao X.   +15 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Structure of the Acidobacteria homodimeric reaction center bound with cytochrome c. [PDF]

Nat Commun, 2022
Dong S, Huang G, Wang C, Wang J, Sui SF, Qin X.   +5 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source