Results 151 to 160 of about 1,600,579 (309)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Site-directed mutagenesis of threonine M222 and tryptophan M252 in the photosynthetic reaction center of Rhodobacter sphaeroides [PDF]

open access: yes, 1990
U. Finkele   +12 more
core   +1 more source

Unstable semiquinone in photosynthetic reaction center [PDF]

open access: yes, 2005
Ubiquinone can take up two electrons and two protons upon reduction and serves as essential redox cofactor in several proteins. Out of its 9 possible redox states, only Q and Q– are seen in the QA site and Q, Q– and QH2 in the Q8 site of the reaction ...
Gerencsér László, Maróti Péter
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Reaction centers of purple bacteria with modified chromophores [PDF]

open access: yes, 1988
Beese, D.   +4 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Center of pressure and vertical ground reaction force parameters.

open access: yes
Center of pressure and vertical ground reaction force parameters.
Wael Maktouf (18189579)   +6 more
core   +1 more source

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