Results 171 to 180 of about 1,600,579 (309)

Role of Small Membrane Proteins in the Green Sulfur Bacterial Reaction Center. [PDF]

ACS Phys Chem Au
Lyratzakis A, Konstantopoulou A, Fragkaki EV, Sousani TI, Karvounis IG, Tsiotis G, Daskalakis V.   +6 more
europepmc   +1 more source

Enhanced Heterogeneous Fenton-like Process for Sulfamethazine Removal via Dual-Reaction-Center Fe-Mo/rGO Catalyst. [PDF]

Nanomaterials (Basel), 2022
Qin W, Ma Y, He T, Hu J, Gao P, Yang S.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Photosynthesis Has Been Established Only Once-Evolution of Photosynthetic Reaction Center Proteins and Bacteriochlorophyll Biosynthesis. [PDF]

Curr Issues Mol Biol
Imhoff JF, Kyndt JA.
europepmc   +1 more source

Properties and Crystal Structure of the Cereibacter sphaeroides Photosynthetic Reaction Center with Double Amino Acid Substitution I(L177)H + F(M197)H. [PDF]

Membranes (Basel), 2023
Fufina TY, Selikhanov GK, Gabdulkhakov AG, Vasilieva LG.   +3 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Predicting organic reaction outcomes with weisfeiler-lehman network

, 2019
The prediction of organic reaction outcomes is a fundamental problem in computational chemistry. Since a reaction may involve hundreds of atoms, fully exploring the space of possible transformations is intractable.
Jaakkola, Tommi S, Jin, Wengong, Coley, Connor Wilson, Barzilay, Regina   +3 more
core  

Enzyme association for environmental biotransformation reactions through contrastive learning of reaction center-specific fingerprints. [PDF]

Bioinformatics
Zhang K, Marti TD, Probst SI, Robinson SL, Fenner K.   +4 more
europepmc   +1 more source

Hidden vibronic and excitonic structure and vibronic coherence transfer in the bacterial reaction center. [PDF]

Sci Adv, 2022
Policht VR, Niedringhaus A, Willow R, Laible PD, Bocian DF, Kirmaier C, Holten D, Mančal T, Ogilvie JP.   +8 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source