Results 181 to 190 of about 1,600,579 (309)

Light harvesting mechanism of the multi-pigment reaction center with three chlorophyll species adapted to both visible and far-red light. [PDF]

Photosynth Res
Shimooka W, Kitoh-Nishioka H, Itoh S, Kimura A.   +3 more
europepmc   +1 more source

Exciton transfer between LH1 antenna complex and photosynthetic reaction center dimer. [PDF]

J Biol Phys, 2021
Pudlák M, Pinčák R.
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Structural basis for aerobic anoxygenic photosynthesis in the reaction center-light-harvesting 1 (RC-LH1) supercomplex of Dinoroseobacter shibae. [PDF]

Commun Biol
Liu ZK, Li JX, Zhang YY, Lv JL, Li K, Chen XL, Zhang YZ, Liu LN, Wang P.   +8 more
europepmc   +1 more source

Dependence of the rate-limiting steps in the dark-to-light transition of photosystem II on the lipidic environment of the reaction center. [PDF]

Photosynthetica, 2022
Magyar M, Akhtar P, Sipka G, Han W, Li X, Han G, Shen JR, Lambrev PH, Garab G.   +8 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Unveiling the charge transport blockade in the D2 branch of the photosystem II reaction center. [PDF]

Proc Natl Acad Sci U S A
Mandal AK, Basera S, Goddard WA, Maiti PK.   +3 more
europepmc   +1 more source

Spatial Separation of Plasmonic Hot-Electron Generation and a Hydrodehalogenation Reaction Center Using a DNA Wire. [PDF]

ACS Nano, 2021
Kogikoski S, Dutta A, Bald I.
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Microscopic basis of reaction center modulation in PsbA variants of photosystem II. [PDF]

Proc Natl Acad Sci U S A
Bhattacharjee S, Gordiy I, Sirohiwal A, Pantazis DA.   +3 more
europepmc   +1 more source