Results 191 to 200 of about 1,600,579 (309)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

High-temperature rate constant measurement for the reaction of GVL with OH

, 2017
-Valerolactone (GVL) is a promising bio-based platform molecule. Hydrogen (H) abstraction is the main consumption pathway for GVL at intermediate to high temperature conditions.
KHALED, Fethi, Farooq, Aamir, Liu, D.
core  

Barrierless Electron Transfer in a Photosynthetic Reaction Center Model. [PDF]

Angew Chem Int Ed Engl
Ullrich T, Ramírez-Wierzbicki I, Slep LD, Cadranel A.   +3 more
europepmc   +1 more source

X-ray structure of the Rhodobacter sphaeroides reaction center with an M197 Phe→His substitution clarifies the properties of the mutant complex. [PDF]

IUCrJ, 2022
Selikhanov G, Fufina T, Guenther S, Meents A, Gabdulkhakov A, Vasilieva L.   +5 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

The Recombination Triplet State in the Far-Red Light Adapted Photosystem II Is Located at the Chl_D1 Site and Resides on the Red-Most Chlorophyll of the Reaction Center. [PDF]

J Phys Chem Lett
Calcinoni A, Casazza AP, Viola S, Agostini A, Carbonera D, Santabarbara S.   +5 more
europepmc   +1 more source

Electronic Structure Effects Related to the Origin of the Remarkable Near-Infrared Absorption of Blastochloris viridis' Light Harvesting 1-Reaction Center Complex. [PDF]

J Chem Theory Comput, 2022
Mondragón-Solórzano G, Sandoval-Lira J, Nochebuena J, Cisneros GA, Barroso-Flores J.   +4 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Mining Thermophile Photosynthesis Genes: A Synthetic Operon Expressing <i>Chloroflexota</i> Species Reaction Center Genes in <i>Rhodobacter sphaeroides</i>. [PDF]

Biomolecules
Rehman Y, Kim Y, Tong M, Blaby IK, Blaby-Haas CE, Beatty JT.   +5 more
europepmc   +1 more source

Photoprotective energy quenching in the red alga Porphyridium purpureum occurs at the core antenna of the photosystem II but not at its reaction center. [PDF]

J Biol Chem, 2022
Fang Y, Liu D, Jiang J, He A, Zhu R, Tian L.   +5 more
europepmc   +1 more source