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Reactive Oxygen and Reactive Nitrogen Species in the Lung
2000Reactive oxygen species (ROS) and reactive nitrogen species (RNS) have been implicated as contributing to the pathogenesis of a broad spectrum of diseases [1, 2]. Historically, oxygen free radicals were primarily considered to be aggressive species, indeed the superoxide (O 2 .- theory of oxygen toxicity is based on this hypothesis, (reviewed in 3 ...
Gregory J. Quinlan, Nicholas J. Lamb
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Characterization of reactive nitrogen species in allergic asthma
Annals of Allergy, Asthma & Immunology, 2014To investigate the molecular mechanism of reactive nitrogen species (RNS) in the pathogenesis of asthma and examine the use of fractional exhaled nitric oxide (FENO) measurements in close conjunction with standard clinical assessments of asthma.Through PubMed, Google Scholar, and Medline databases, a broad medical literature review was performed in the
Li, Zuo +2 more
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Reactive Oxygen and Nitrogen Species
2004The term “radical” is often used loosely in chemistry to refer to various groups of atoms that behave as a unit, such as the carbonate radical (CO 3 sup2- ), nitrate radical (NO 3 sup- ), and the methyl radical (CH3p-). According to this definition, Lavoisier (1789) has already indicated that the four elements: phosphorus, sulphur, carbon, and hydrogen
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Pindolol is a potent scavenger of reactive nitrogen species
Life Sciences, 2005Pindolol is an indolic drug that has been shown to enhance and/or accelerate selective serotonin specific reuptake inhibitors (SSRI)-induced antidepressant (AD) effect, even though the respective mechanism is still unclear. It has been demonstrated that inhibition of nitric oxide (*NO) synthesis in CNS produces anxiolytic and AD-like behavioural ...
Eduarda, Fernandes +3 more
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Imaging of Intracellular Reactive Nitrogen Species and Reactive Sulfur Species
2020This chapter summarizes representative small-molecule fluorescent probes for reactive nitrogen species and reactive sulfur species in living cells. The design and response mechanisms of the probes are described in detail. Probes that have not been applied in living cell analysis are not included.
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[Reactive nitrogen and oxygen species].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2010Reactive nitrogen species (RNS) and reactive oxygen species (ROS) are mainly free radicals which including non-paired electrons. They are constantly formed as side products of biological reactions. They are also generated directly and indirectly by the cells which were exposed to environmental stress, i.e., UV radiation, ionizing radiation ...
Helena, Puzanowska-Tarasiewicz +2 more
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Endocannabinoids and Reactive Nitrogen and Oxygen Species in Neuropathologies
Journal of Neuroimmune Pharmacology, 2006Neuropathologies that affect our population include ischemic stroke and neurodegenerative diseases of immune origin, including multiple sclerosis. The endocannabinoid system in the brain, including agonists anandamide (arachidonyl ethanolamide) and 2-arachidonoylglycerol, and the CB1 and CB2 cannabinoid receptors, has been implicated in the ...
Allyn C, Howlett +2 more
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Reactive oxygen species, reactive nitrogen species and redox signalling
2016This chapter explains our current understanding of how reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated and perceived, and how they propagate their messages. It argues that the main components involved here include those used in phosphorylation and cyclic nucleotides.
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Reactive oxygen and nitrogen species in neurodegeneration
Free Radical Biology and Medicine, 2013Julie K, Andersen +2 more
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