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[Reactive oxygen and nitrogen species].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2012Reactive oxygen and nitrogen species (ROS and RNS respectively) play an important role in the proper functioning of many cellular processes. Generation of reactive oxygen species is an integral part of aerobic metabolism of cells. Their overproduction and subsequent oxidative stress occurs during pathogenesis of many diseases.
Mateusz, Ługowski +3 more
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Characterization of reactive nitrogen species in allergic asthma
Annals of Allergy, Asthma & Immunology, 2014To investigate the molecular mechanism of reactive nitrogen species (RNS) in the pathogenesis of asthma and examine the use of fractional exhaled nitric oxide (FENO) measurements in close conjunction with standard clinical assessments of asthma.Through PubMed, Google Scholar, and Medline databases, a broad medical literature review was performed in the
Li, Zuo +2 more
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Pindolol is a potent scavenger of reactive nitrogen species
Life Sciences, 2005Pindolol is an indolic drug that has been shown to enhance and/or accelerate selective serotonin specific reuptake inhibitors (SSRI)-induced antidepressant (AD) effect, even though the respective mechanism is still unclear. It has been demonstrated that inhibition of nitric oxide (*NO) synthesis in CNS produces anxiolytic and AD-like behavioural ...
Eduarda, Fernandes +3 more
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Reactive Oxygen and Reactive Nitrogen Species in the Lung
2000Reactive oxygen species (ROS) and reactive nitrogen species (RNS) have been implicated as contributing to the pathogenesis of a broad spectrum of diseases [1, 2]. Historically, oxygen free radicals were primarily considered to be aggressive species, indeed the superoxide (O 2 .- theory of oxygen toxicity is based on this hypothesis, (reviewed in 3 ...
Gregory J. Quinlan, Nicholas J. Lamb
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Imaging of Intracellular Reactive Nitrogen Species and Reactive Sulfur Species
2020This chapter summarizes representative small-molecule fluorescent probes for reactive nitrogen species and reactive sulfur species in living cells. The design and response mechanisms of the probes are described in detail. Probes that have not been applied in living cell analysis are not included.
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Reactive Oxygen and Nitrogen Species
2004The term “radical” is often used loosely in chemistry to refer to various groups of atoms that behave as a unit, such as the carbonate radical (CO 3 sup2- ), nitrate radical (NO 3 sup- ), and the methyl radical (CH3p-). According to this definition, Lavoisier (1789) has already indicated that the four elements: phosphorus, sulphur, carbon, and hydrogen
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[Reactive nitrogen and oxygen species].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2010Reactive nitrogen species (RNS) and reactive oxygen species (ROS) are mainly free radicals which including non-paired electrons. They are constantly formed as side products of biological reactions. They are also generated directly and indirectly by the cells which were exposed to environmental stress, i.e., UV radiation, ionizing radiation ...
Helena, Puzanowska-Tarasiewicz +2 more
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The interdependence of the reactive species of oxygen, nitrogen, and carbon
Journal of Physiology and Biochemistry, 2012This mini-review tries to summarize the main interdependences between the free radicals of oxygen, nitrogen, and carbon. Also, the main metabolic pathways for these radical species are described, as well as how these affect their interaction and functional implications.
Walther, Bild +3 more
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Reactive nitrogen and oxygen species in airway inflammation
European Journal of Pharmacology, 2001The free radical nitric oxide (NO) is an important mediator of many biological processes. Interestingly, the molecule appears to be a two-edged sword. Apart from NO having a function as a paracrine messenger, NO-derived oxidants are important weapons against invading pathogens. The role of NO in the airways is similarly ambiguous. Besides the task as a
Folkerts, G. +3 more
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Regulation of ryanodine receptors by reactive nitrogen species
Biochemical Pharmacology, 1999The ryanodine receptors (RyRs) are large intracellular calcium release channels that play an important role in the control of the calcium levels in excitable and non-excitable cells. Many endogenous modulators such as Mg2+, ATP, or calmodulin can affect the channel activities of the three known mammalian RyR isoforms.
J P, Eu +3 more
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