Results 71 to 80 of about 548,863 (305)

Plasma functionalized surface of commodity polymers for dopamine detection [PDF]

, 2017
We have fabricated potentially generalizable sensors based on polymeric-modified electrodes for the electrochemical detection of dopamine. Sensitive and selective sensors have been successfully obtained by applying a cold-plasma treatment during 1–2 min ...
Alemán Llansó, Carlos, Armelín Diggroc, Elaine Aparecida, Buendía Morales, Jorge Juan, Castedo Rodríguez, Alejandra, Fabregat Jové, Georgina, Llorca Piqué, Jordi, Osorio Madrigal, Joaquin   +6 more
core   +2 more sources

Reactive oxygen and nitrogen species in pulmonary hypertension [PDF]

Free Radical Biology and Medicine, 2012
Pulmonary vascular disease can be defined as either a disease affecting the pulmonary capillaries and pulmonary arterioles, termed pulmonary arterial hypertension, or a disease affecting the left ventricle, called pulmonary venous hypertension. Pulmonary arterial hypertension (PAH) is a disorder of the pulmonary circulation characterized by endothelial
Diana M, Tabima, Sheila, Frizzell, Mark T, Gladwin   +2 more
openaire   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Oxidative Stress Resulting From Helicobacter pylori Infection Contributes to Gastric Carcinogenesis. [PDF]

, 2017
Helicobacter pylori is a gram-negative, microaerophilic bacterium that infects the stomach and can lead to, among other disorders, the development of gastric cancer. The inability of the host to clear the infection results in a chronic inflammatory state
Butcher, Lindsay D, Crowe, Sheila E, den Hartog, Gerco, Ernst, Peter B   +3 more
core   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Dietary Antioxidant An Indispensible Nutrient

Journal of Bahria University Medical and Dental College, 2019
Free radicals prevail as atoms, molecules or unpaired electrons being extremely reactive as well as unstable1. They can lead to chemical reactions alongside different molecules.
Shizma Junejo, Zara Sami, Faiza Rafique Shaikh   +2 more
doaj   +1 more source

Ground‐based measurements of NOx and total reactive oxidized nitrogen (NOy) at Sable Island, Nova Scotia, during the NARE 1993 summer intensive [PDF]

, 1996
Measurements of NO, NO2, and total reactive oxidized nitrogen (NOy) were added to ongoing measurements of aerosols, CO, and O3 at Sable Island (43°55′N, 60°01′W), Nova Scotia, during the North Atlantic Regional Experiment (NARE) 1993 summer intensive ...
Albercook, G. M., Carroll, M. A., Duderstadt, Katharine A., Fehsenfeld, F. C., Forbes, G., Holloway, J. S., Markevitch, A. N., Ogren, J., Owens, K. R., Parrish, D. D., Wang, T.   +10 more
core   +2 more sources

Redox stress defines the small artery vasculopathy of hypertension: how do we bridge the bench-to-bedside gap? [PDF]

, 2017
Although convincing experimental evidence demonstrates the importance of vascular reactive oxygen and nitrogen species (RONS), oxidative stress, and perturbed redox signaling as causative processes in the vasculopathy of hypertension, this has not ...
Liang, Mingyu, Montezano, Augusto C., Rios, Francisco, Touyz, Rhian M., Widlansky, Michael E.   +4 more
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source