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Reactive oxygen species, health and longevity [PDF]

AIMS Molecular Science, 2016
Reactive oxygen species (ROS) are considered responsible of ageing in animal and humans. Mitochondria are both source and target of ROS. Various strategies to reduce ROS production have been considered to extend lifespan.
Vittorio Emanuele Bianchi, Giancarlo Falcioni   +1 more
doaj   +4 more sources

Reactive oxygen species, apoptosis and cancer [PDF]

Vojnosanitetski Pregled, 2013
Projekat Ministarstva nauke Republike Srbije, br ...
Stojnev Slavica, Ristić-Petrović Ana, Janković-Veličković Ljubinka   +2 more
doaj   +3 more sources

Reactive Oxygen Species in Cystic Kidney Disease [PDF]

Antioxidants
Polycystic kidney disease (PKD) is a rare but significant renal condition with major implications for global acute and chronic patient care. Oxidative stress and reactive oxygen species (ROS) can significantly alter its pathophysiology, clinical outcomes,
Sanat Subhash, Sonya Vijayvargiya, Aetan Parmar, Jazlyn Sandhu, Jabrina Simmons, Rupesh Raina   +5 more
doaj   +2 more sources

Respiratory Viruses and Virus-like Particle Vaccine Development: How Far Have We Advanced?

Viruses, 2023
With technological advancements enabling globalization, the intercontinental transmission of pathogens has become much easier. Respiratory viruses are one such group of pathogens that require constant monitoring since their outbreak leads to massive ...
Ki-Back Chu, Fu-Shi Quan
doaj   +1 more source

Glutathione Peroxidase 8 Suppression by Histone Deacetylase Inhibitors Enhances Endoplasmic Reticulum Stress and Cell Death by Oxidative Stress in Hepatocellular Carcinoma Cells

Antioxidants, 2021
Histone deacetylase inhibitors (HDACi) are emerging as anti-hepatocellular carcinoma (HCC) agents. However, the molecular mechanisms underlying HDACi-induced sensitization to oxidative stress and cell death of HCC remain elusive.
Hae-Ahm Lee, Ki-Back Chu, Eun-Kyung Moon, Fu-Shi Quan   +3 more
doaj   +1 more source

Advances in Toxoplasma gondii Vaccines: Current Strategies and Challenges for Vaccine Development

Vaccines, 2021
Toxoplasmosis, caused by the apicomplexan parasite Toxoplasma gondii, is one of the most damaging parasite-borne zoonotic diseases of global importance.
Ki-Back Chu, Fu-Shi Quan
doaj   +1 more source

Influenza Virus-like Particle (VLP) Vaccines Expressing the SARS-CoV-2 S Glycoprotein, S1, or S2 Domains

Vaccines, 2021
The ongoing severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic had brought disastrous consequences throughout the entire world. While several manufactured vaccines have been approved for emergency use, continuous efforts to generate ...
Ki-Back Chu, Hae-Ji Kang, Keon-Woong Yoon, Hae-Ahm Lee, Eun-Kyung Moon, Beom-Ku Han, Fu-Shi Quan   +6 more
doaj   +1 more source

Sublingual Vaccination with Live Influenza Virus Induces Better Protection Than Oral Immunization in Mice

Life, 2022
Both sublingual (SL) and oral vaccine administration modalities are convenient, easy, and safe. Here, we have investigated the differences in vaccine efficacy that are induced by oral and sublingual immunization with live influenza virus (A/Hong Kong/1 ...
Jie Mao, Gi-Deok Eom, Keon-Woong Yoon, Hae-Ji Kang, Ki-Back Chu, Fu-Shi Quan   +5 more
doaj   +1 more source

Recombinant Vaccinia Virus Expressing Plasmodium berghei Apical Membrane Antigen 1 or Microneme Protein Enhances Protection against P. berghei Infection in Mice

Tropical Medicine and Infectious Disease, 2022
Recombinant vaccinia viruses (rVV) are effective antigen delivery vectors and are researched widely as vaccine platforms against numerous diseases. Apical membrane antigen 1 (AMA1) is one of the candidate antigens for malaria vaccines but rising concerns
Min-Ju Kim, Ki-Back Chu, Su-Hwa Lee, Hae-Ji Kang, Keon-Woong Yoon, Md Atique Ahmed, Fu-Shi Quan   +6 more
doaj   +1 more source

Preliminary Trichinella spiralis Infection Ameliorates Subsequent RSV Infection-Induced Inflammatory Response

Cells, 2020
Respiratory syncytial virus (RSV) infection affects the lives of neonates throughout the globe, causing a high rate of mortality upon hospital admission. Yet, therapeutic options to deal with this pulmonary pathogen are currently limited.
Ki-Back Chu, Hae-Ahm Lee, Hae-Ji Kang, Eun-Kyung Moon, Fu-Shi Quan   +4 more
doaj   +1 more source