Results 61 to 70 of about 1,166,114 (226)
Oxygen depletion in FLASH ultra-high-dose-rate radiotherapy: A molecular dynamics simulation [PDF]
, 2020 We present a first-principles molecular dynamics (MD) simulation and expound upon a mechanism of oxygen depletion hypothesis to explain the mitigation of normal tissue injury observed in ultra-high-dose-rate (UHDR) FLASH radiotherapy. We simulated damage to a segment of DNA (also representing other bio-molecules such as RNA and proteins) in a ...
arxiv +1 more source
Respiratory ResearchExcessive pulmonary inflammation is the hallmark of respiratory syncytial virus (RSV) infection hindering efficacious RSV vaccine development. Yet, the vast majority of the experimental RSV vaccine studies use laboratory-adapted RSV strains that do not ...
Min-Ju Kim +7 more
doaj +1 more source
Heliyon, 2020 Legionella grows intracellularly in free-living amoeba as well as in mammalian macrophages. Until now, the overall gene expression pattern of intracellular Legionella in Acanthamoeba was not fully explained. Intracellular bacteria are capable of not only
Fu-Shi Quan +4 more
doaj
A quantum protective mechanism in photosynthesis [PDF]
Scientific Reports 5, Article number: 8720 (2015), 2016 Since the emergence of oxygenic photosynthesis, living systems have developed protective mechanisms against reactive oxygen species. During charge separation in photosynthetic reaction centres, triplet states can react with molecular oxygen generating destructive singlet oxygen.
arxiv +1 more source
Reactive oxygen species and sperm cells
Reproductive Biology and Endocrinology, 2004 There is a dynamic interplay between pro- and anti-oxidant substances in human ejaculate. Excessive reactive oxygen species (ROS) generation can overwhelm protective mechanism and initiate changes in lipid and/or protein layers of sperm plasma membranes.
Kurpisz Maciej, Sanocka Dorota
doaj +1 more source
Decreased Aquaporin 4 and 6 mRNAs in Patients With Chronic Otitis Media With Otorrhea [PDF]
Clinical and Experimental Otorhinolaryngology, 2019 Objectives Aquaporins (AQPs) are integral membrane proteins engaged in the modulation of water homeostasis, but the roles they play in chronic otitis media (COM) have not been well investigated.
Ji Hoon Kim +5 more
doaj +1 more source
Neutrophil-derived reactive oxygen species promote tumor colonization
Communications Biology, 2021 Zhong et al. investigate how mutations in the NOX2 subunit Ncf1 lead to reduced ROS formation and affect B16F10 lung metastasis. The study highlights neutrophils as key to detrimental ROS-formation and suggest the involvement of IL-1 beta and RAGE.
Jianghong Zhong +3 more
doaj +1 more source
Reactive oxygen species in plant development [PDF]
, 2018 Reactive oxygen species (ROS) are produced by metabolic pathways in almost all cells. As signaling components, ROS are best known for their roles in abiotic and biotic stress-related events.
M'Hamdi, Amna, Van Breusegem, Frank
core +2 more sources
Moving Forwards by Blocking Back-Flow: The Yin and Yang of MI Therapy. [PDF]
, 2016 Mitochondrial reactive oxygen species production has emerged as an important pathological mechanism in myocardial ischemia/reperfusion injury. Attempts at targeting reactive oxygen species by scavenging using antioxidants have, however, been clinically ...
Brookes, Paul S +4 more
core +2 more sources
Imaging Reactive Oxygen Species in Arthritis
Molecular Imaging, 2004 Reactive oxygen species (ROS) have been shown to play a role in the pathogenesis of arthritides. Luminol was used as the primary reporter of ROS and photons resulting from the chemiluminescence reaction were detected using a super-cooled CCD photon ...
Wei-Tsung Chen +2 more
doaj +1 more source