Results 91 to 100 of about 267,926 (301)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

The Alternate Arm Converter: A New Hybrid Multilevel Converter With DC-Fault Blocking Capability

open access: yes, 2013
This paper explains the working principles, supported by simulation results, of a new converter topology intended for HVDC applications, called the alternate arm converter (AAC).
Critchley, R   +6 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Paper making from bagasse [PDF]

open access: yes, 2020
Though the revolution of technology has reduced paper production everywhere around the world, the amount of paper consumed each day is still tremendously large.
Abu Bakar Sidik, Dilaeleyana   +7 more
core  

Power Quality Improvement Wind Energy System Using Cascaded Multilevel Inverter [PDF]

open access: yes, 2013
In this paper, a wind energy conversion system based on a cascaded H-bridge multilevel inverter (CHBMLI) topology has been proposed to be used for the grid interface of large split winding alternators (SWAs).
A. S., Kumar, J.S., Sathiyanarayanan
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Modular multilevel converter with modified half-bridge submodule and arm filter for dc transmission systems with DC fault blocking capability [PDF]

open access: yes, 2018
Although a modular multilevel converter (MMC) is universally accepted as a suitable converter topology for the high voltage dc transmission systems, its dc fault ride performance requires substantial improvement in order to be used in critical ...
Abdelsalam, Ibrahim A.   +3 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Hybrid HVDC for supply of power to offshore oil platforms [PDF]

open access: yes, 2004
A HVDC hybrid system, comprising a line commutated thyristor HVDC converter and a STATCOM, is proposed in this paper for supplying power to offshore oil platforms that do not have their own generation. The proposed system combines the robust performance,
Andersen, B., Cartwright, P., Xu, L.
core  

Nonlinear finite element analysis of reinforced concrete beams strengthened with textile fine grained mortar [PDF]

open access: yes, 2020
Nowadays, there was an increasing need of repairing and upgrading the reinforced concrete (RC) structure due to the deterioration of the structure. The fibre reinforced polymer (FRP) was commonly used for structural retrofitting purposes.
Abdul Hamid, Noor Azlina   +4 more
core  

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