Results 71 to 80 of about 277,373 (307)

Selective compensation of reactive, unbalance, and distortion power in smart grids by synergistic control of distributed switching power interfaces

open access: yes, 2013
Smart grids feature distributed energy resources interfaced to the grid by means of switching power converters. Synergistic control of these units can considerably increase the distribution efficiency and power quality by limiting the unbalance, reactive
E. Verri Liberado   +7 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Distributed control algorithm for optimal reactive power control in power grids

open access: yesInternational Journal of Electrical Power & Energy Systems, 2016
Abstract Reactive power generation has been commonly used for power loss minimization and voltage profile improvement in power systems. However, the opportunity cost of reactive power generation should be considered since it affects the frequency control capability of the generator to some degree.
Irfan Khan   +3 more
openaire   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Voltage Control Method for Active Distribution Networks Based on Regional Power Coordination

open access: yesEnergies, 2019
As loads connected to active distribution network (ADN) grow, ADN’s voltage safety issues are becoming more serious. At present, the solution is mainly to build more distributed generation (DG) or to adjust the reactive power in the whole network ...
Jin-Xin Ou-Yang   +4 more
doaj   +1 more source

Local Voltage Control in Distribution Networks using PI Control of Active and Reactive Power [Elektronisk resurs]

open access: yes, 2022
Overvoltage is becoming increasingly prevalent in distribution networks with high penetration of renewable distributed energy sources (DERs). Local control of converter-based resources is a flexible and scalable method to prevent this growing issue ...
Lundberg, Martin,   +3 more
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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