Reactive Oxygen and Sulfur Species: Partners in Crime
The emergence of complexity requires cooperation, yet selection typically favors defectors that do not cooperate. Such evolutionary conflict can be alleviated by a variety of mechanisms, allowing complexity to emerge.
Neil W. Blackstone
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Regulation of redox signaling by reactive sulfur species. [PDF]
Reactive sulfur species, such as cysteine persulfide, are produced endogenously at significant levels in cells and have rapidly emerged as common biomolecules. By virtue of improved analytical methods for detecting reactive persulfides, it has been demonstrated that these reactive molecules exhibit unique chemical properties and are present in various ...
Kasamatsu S, Ihara H.
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Reactive Sulfur Species (RSS) in Physiological and Pathological Conditions and in Therapy [PDF]
Sulfur is a multivalent and nonmetallic chemical element with the symbol S and the atomic number 16 [...]
Anna Bilska-Wilkosz, Małgorzata Iciek
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Sensing and regulation of reactive sulfur species (RSS) in bacteria. [PDF]
The infected host deploys generalized oxidative stress caused by small inorganic reactive molecules as antibacterial weapons. An emerging consensus is that hydrogen sulfide (H2S) and forms of sulfur with sulfur-sulfur bonds termed reactive sulfur species (RSS) provide protection against oxidative stressors and antibiotics, as antioxidants.
Giedroc DP +3 more
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Reactive sulfur species as emerging immunomodulators: mechanistic insights and therapeutic prospects [PDF]
Inflammation is a vital component of host defense and tissue repair, but its dysregulation contributes to chronic metabolic and immune-mediated diseases.
Youbang Chen +5 more
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Cystine-dependent antiporters buffer against excess intracellular reactive sulfur species-induced stress [PDF]
Reactive sulfur species (RSS) play a role in redox homeostasis; however, adaptive cell responses to excessive intracellular RSS are not well understood. Therefore, in this study, we generated transgenic (Tg) mice overexpressing cystathionine gamma-lyase (
Masahiro Akiyama +11 more
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The Reactive Sulfur Species Concept: 15 Years On. [PDF]
Fifteen years ago, in 2001, the concept of “Reactive Sulfur Species” or RSS was advocated as a working hypothesis. Since then various organic as well as inorganic RSS have attracted considerable interest and stimulated many new and often unexpected avenues in research and product development. During this time, it has become apparent that molecules with
Giles GI, Nasim MJ, Ali W, Jacob C.
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Reactive Sulfur Species Interact with Other Signal Molecules in Root Nodule Symbiosis in Lotus japonicus [PDF]
Reactive sulfur species (RSS) function as strong antioxidants and are involved in various biological responses in animals and bacteria. Few studies; however, have examined RSS in plants.
Mitsutaka Fukudome +7 more
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Geminal-dithiol-based precursors for reactive sulfur species.
The chemistry and reactivity of a free gem-dithiol, 1,3-diphenylpropane-2,2-dithiol, and its derivatives (S-nitrosothiol and dithiirane) are studied. These compounds can release H2S, NO, or induce S-persulfidation.
Xu S +5 more
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Small molecule generators of biologically reactive sulfur species. [PDF]
Reactive sulfur species (RSS) are integral to cellular survival and growth. Here, small molecule generators of RSS are reviewed.
Bora P +3 more
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