Adaptation of Candida albicans to Reactive Sulfur Species. [PDF]
Abstract Candida albicans is an opportunistic fungal pathogen that is highly resistant to different oxidative stresses. How reactive sulfur species (RSS) such as sulfite regulate gene expression and the role of the transcription factor Zcf2 and the sulfite exporter Ssu1 in such responses are not known. Here, we show that C.
Chebaro Y +4 more
europepmc +4 more sources
Catalase as a sulfide-sulfur oxido-reductase: An ancient (and modern?) regulator of reactive sulfur species (RSS) [PDF]
Catalase is well-known as an antioxidant dismutating H2O2 to O2 and H2O. However, catalases evolved when metabolism was largely sulfur-based, long before O2 and reactive oxygen species (ROS) became abundant, suggesting catalase metabolizes reactive ...
Kenneth R. Olson +6 more
doaj +2 more sources
Redox signaling regulated by electrophiles and reactive sulfur species. [PDF]
Redox signaling is a key modulator of oxidative stress induced by nonspecific insults of biological molecules generated by reactive oxygen species. Current redox biology is revisiting the traditional concept of oxidative stress, such that toxic effects of reactive oxygen species are protected by diverse antioxidant systems upregulated by oxidative ...
Nishida M +5 more
europepmc +4 more sources
Sulfide Homeostasis and Nitroxyl Intersect via Formation of Reactive Sulfur Species in
Staphylococcus aureus is a commensal human pathogen and a major cause of nosocomial infections. As gaseous signaling molecules, endogenous hydrogen sulfide (H2S) and nitric oxide (NO·) protect S.
Hui Peng +10 more
doaj +2 more sources
Highlighted mechanistic aspects in the chemical biology of reactive sulfur species. [PDF]
Linked ArticlesThis article is part of a themed section on Chemical Biology of Reactive Sulfur Species. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v176.4 ...
Nagy P, Schwarz G, Kopriva S.
europepmc +4 more sources
Reactive Sulfur Species in Human Diseases
Significance: Reactive sulfur species (RSS) have been recently recognized as redox molecules no less important than reactive oxygen species or reactive nitrogen species. They possess regulatory and protective properties and are involved in various metabolic processes, thereby contributing to the maintenance of human health.
Małgorzata Iciek +3 more
openaire +4 more sources
Recent Development of the Molecular and Cellular Mechanisms of Hydrogen Sulfide Gasotransmitter
Hydrogen sulfide has been recently identified as the third biological gasotransmitter, along with the more well studied nitric oxide (NO) and carbon monoxide (CO). Intensive studies on its potential as a therapeutic agent for cardiovascular, inflammatory,
Jianyun Liu +7 more
doaj +1 more source
Activity-Based Fluorescent Probes for Hydrogen Sulfide and Related Reactive Sulfur Species. [PDF]
Fosnacht KG, Pluth MD.
europepmc +2 more sources
Rhodanese Rdl2 produces reactive sulfur species to protect mitochondria from reactive oxygen species
Mitochondria damage is related to a broad spectrum of pathologies including Alzheimer's, Parkinson's disease, and carcinogenesis. Recently, it has been found that reactive sulfur species (RSS) has a close connection with mitochondrial health.
Qingda Wang +6 more
openaire +2 more sources
Even under optimal conditions many metabolic processes produce ROS like superoxide anion (O2.-), hydrogen peroxide (H2O2) and hydroxyl radicals (OH⋅), particularly in chloroplast and mitochondria.
Divya Singh
doaj +1 more source

