Results 51 to 60 of about 3,044 (235)

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

The SOD1 Inhibitor, LCS-1, Oxidizes H2S to Reactive Sulfur Species, Directly and Indirectly, through Conversion of SOD1 to an Oxidase

Antioxidants
LCS-1, a putative selective inhibitor of SOD1, is a substituted pyridazinone with rudimentary similarity to quinones and naphthoquinones. As quinones catalytically oxidize H2S to biologically active reactive sulfur species (RSS), we hypothesized LCS-1 ...
Kenneth R. Olson, Tsuyoshi Takata, Kasey J. Clear, Yan Gao, Zhilin Ma, Ella Pfaff, Karthik Mouli, Thomas A. Kent, Prentiss Jones, Jon Fukuto, Gang Wu, Karl D. Straub   +11 more
doaj   +1 more source

Air Pollution and the Risk and Progression of Multiple Sclerosis: A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley   +1 more source

Cystine-dependent antiporters buffer against excess intracellular reactive sulfur species-induced stress

Redox Biology, 2022
Reactive sulfur species (RSS) play a role in redox homeostasis; however, adaptive cell responses to excessive intracellular RSS are not well understood. Therefore, in this study, we generated transgenic (Tg) mice overexpressing cystathionine gamma-lyase (
Masahiro Akiyama, Takamitsu Unoki, Hanako Aoki, Akiyuki Nishimura, Yasuhiro Shinkai, Eiji Warabi, Kazuhiro Nishiyama, Yuka Furumoto, Naohiko Anzai, Takaaki Akaike, Motohiro Nishida, Yoshito Kumagai   +11 more
doaj   +1 more source

Effect of reactive sulfur removal by activated carbon on aviation fuel thermal stability [PDF]

, 2020
The effect of reactive sulfur removal from a Jet A-1 fuel with marginal thermal 3 stability on surface deposition propensity is reported. The sulfur removal was achieved 4 through adsorptive treatment the fuel with activated carbon.The treated fuel was ...
Sheikhansari, A., Gadsby, Phil, Blakey, S.G., Sheikhansari, Abdolkarim, Blakey, Simon G.; id_orcid, Pourkashanian, Mohammed, Alborzi, E., Gadsby, P., Alborzi, Ehsan, Parks, Christopher M., Pourkashanian, M., Parks, C.M.   +11 more
core   +1 more source

Reduction of Oxide Inclusions During the High‐Frequency Welding of Steel via a Nonthermal Ar/H2 Plasma Jet

Advanced Engineering Materials, EarlyView.
High‐frequency (HF) welding of steel is limited by oxide inclusions that degrade weld quality. This study demonstrates, for the first time, the integration of a nonthermal Ar/H2 dielectric barrier discharge (DBD) plasma jet into HF welding. Local plasma treatment provides effective shielding and in‐situ oxide reduction, resulting in markedly fewer and ...
Viktor Udachin, Lienhard Wegewitz, René Gustus, Henning Wiche, Wolfgang Maus‐Friedrichs   +4 more
wiley   +1 more source

Hydropersulfides (RSSH) attenuate doxorubicin-induced cardiotoxicity while boosting its anticancer action

Redox Biology, 2023
Cardiotoxicity is a frequent and often lethal complication of doxorubicin (DOX)-based chemotherapy. Here, we report that hydropersulfides (RSSH) are the most effective reactive sulfur species in conferring protection against DOX-induced toxicity in H9c2 ...
Blaze M. Pharoah, Chengximeng Zhang, Vinayak S. Khodade, Gizem Keceli, Christopher McGinity, Nazareno Paolocci, John P. Toscano   +6 more
doaj   +1 more source

SNF1-related protein kinases type 2 are involved in plant responses to cadmium stress [PDF]

, 2012
Cadmium ions are notorious environmental pollutants. In order to adapt to cadmium-induced deleterious effects plants have developed sophisticated defense mechanisms.
Wawer, Izabela, Kulik, Anna, Anielska-Mazur, Anna, Bucholc, Maria, Dobrowolska, Grażyna, Krzywińska, Ewa, Szymańska, K   +6 more
core  

Cold physical plasma-induced oxidation of cysteine yields reactive sulfur species (RSS) [PDF]

, 2019
Purpose: Studying plasma liquid chemistry can reveal insights into their biomedical effects, i.e. to understand the direct and indirect processes triggered by the treatment in a model or clinical application.
Bruno, Giuliana, Woedtke, Thomas von, Weltmann, Klaus-Dieter, Wende, Kristian, Heusler, Thea, Lackmann, Jan-Wilm   +5 more
core   +1 more source

Redox signaling regulated by electrophiles and reactive sulfur species

Journal of Clinical Biochemistry and Nutrition, 2016
Redox signaling is a key modulator of oxidative stress induced by nonspecific insults of biological molecules generated by reactive oxygen species. Current redox biology is revisiting the traditional concept of oxidative stress, such that toxic effects of reactive oxygen species are protected by diverse antioxidant systems upregulated by oxidative ...
Nishida, Motohiro, Kumagai, Yoshito, Ihara, Hideshi, Fujii, Shigemoto, Motohashi, Hozumi, Akaike, Takaaki   +5 more
openaire   +3 more sources