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Comment on "Reactogenicity Study of mRNA COVID-19 Vaccine"

open access: yesArchivos de Prevención de Riesgos Laborales, 2023
Dear Editor, we would like to share ideas on the publication “Reactogenicity Study of mRNA Vaccines Against COVID-19.” Inglés Torruella et al. compare the reactogenicity of two types of mRNA vaccines against COVID-19, Commirnaty® (Pfizer) and Spikevax ...
Amnuay Kleebayoon, Viroj Wiwanitkit
core   +6 more sources

Outer membrane vesicles: moving within the intricate labyrinth of assays that can predict risks of reactogenicity in humans

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Outer membrane vesicles (OMV) are exosomes naturally released from the surface of Gram-negative bacteria. Since the ’80s, OMVs have been proposed as powerful vaccine platforms due to their intrinsic self-adjuvanticity and ability to present multiple ...
Omar Rossi   +2 more
doaj   +2 more sources

Reactogenicity to a Live Attenuated Varicella Vaccine in Canadian Children [PDF]

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2000
OBJECTIVE: To assess the reactogenicity and safety of a thermostable, high titre, varicella vaccine in healthy infants and ...
Scott A Halperin   +3 more
core   +5 more sources

Systemic reactogenicity is a correlate of MF59 adjuvant-moderated immunogenicity in influenza vaccinated children

open access: yesJournal of Clinical Virology Plus
Background: Adjuvanted influenza vaccine induces more robust antibody responses, but is associated with more adverse events following vaccination. Prior work has examined the link between vaccine reactions and immunogenicity in adults, but little is ...
Charlotte Switzer   +4 more
doaj   +2 more sources

Reactogenicity after heterologous and homologous COVID-19 prime-boost vaccination regimens: descriptive interim results of a comparative observational cohort study

open access: yesBMC Infectious Diseases, 2022
Background Due to safety signals after vaccination with COVID-19 vector vaccines, several states recommended to complete the primary immunization series in individuals having received one dose of ChAdOx1 (AstraZeneca) with an mRNA vaccine.
Lisette Warkentin   +8 more
doaj   +2 more sources

Innate Responses to the Former COVID-19 Vaccine Candidate CVnCoV and Their Relation to Reactogenicity and Adaptive Immunogenicity

open access: yesVaccines
Vaccines are highly effective at preventing severe coronavirus disease (COVID-19). With mRNA vaccines, further research is needed to understand the association between immunogenicity and reactogenicity, which is defined as the physical manifestation of ...
Olaf-Oliver Wolz   +14 more
doaj   +2 more sources

Rapid assessment of the reactogenicity of a 2016-2017 seasonal influenza vaccine: results from a feasibility study

open access: yesExpert Review of Vaccines, 2017
Background: ​​The European Medicines Agency (EMA) calls for a strategy for enhanced safety surveillance of seasonal influenza vaccines. Objective: We assessed the feasibility of collecting reactogenicity data within one month of the start of the ...
Anke L. Stuurman   +2 more
doaj   +2 more sources

Association between Reactogenicity and Immunogenicity after Vaccination with BNT162b2 [PDF]

open access: yesVaccines, 2021
It is not clear whether there is an association between adverse reactions and immune response after vaccination. Seven hundred and thirty-five vaccinees from our University Medical Center vaccination clinic provided information about sex, age and adverse
Stilla Bauernfeind   +8 more
doaj   +4 more sources

The how’s and what’s of vaccine reactogenicity [PDF]

open access: yesnpj Vaccines, 2019
AbstractReactogenicity represents the physical manifestation of the inflammatory response to vaccination, and can include injection-site pain, redness, swelling or induration at the injection site, as well as systemic symptoms, such as fever, myalgia, or headache.
Caroline Hervé   +4 more
openaire   +3 more sources

Immunogenicity and Reactogenicity in Q Fever Vaccine Development

open access: yesFrontiers in Immunology, 2022
Coxiella burnetiiis an obligate intracellular bacterium which, in humans, causes the disease Q fever. Although Q fever is most often a mild, self-limiting respiratory disease, it can cause a range of severe syndromes including hepatitis, myocarditis, spontaneous abortion, chronic valvular endocarditis, and Q fever fatigue syndrome.
Alycia P. Fratzke   +4 more
openaire   +3 more sources

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