Results 111 to 120 of about 4,232,184 (292)

Letter from Beatrice Webb to Herbert Read, April 10th, 1941

, 1941
Part of a collection of letters between Beatrice Webb (English sociologist, economist, labour historian and social reformer, one of the founders of the London School of Economics and the Fabian Society, and who coined the term "collective bargaining ...
Webb, Beatrice, 1858-1943
core   +1 more source

Tomtit‐Raven Evolutionary Selector‐Reinforced Attention‐Driven: A High‐Performance and Computationally Efficient Cyber Threat Detection Framework for Smart Grids

Energy Science & Engineering
Identifying cyber threats maintains the security and operational stability of smart grid systems because they experience escalating attacks that endanger both operating data reliability and system stability and electricity grid performance.
Priya R. Karpaga, Praveen Kumar Balachandran, Umawathy Techanamurthy, Muhammad Ammirrul Atiqi Mohd Zainuri   +3 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Letter from George Read Jr. to George Read Sr.

This photostat is a copy of a letter written by George Read Junior to George Read Senior. He is writing home with information from Lewis about the legal cases he is working on and when he will be ...
Read Family
core   +2 more sources

Letter to the editor: radiomics signature for dynamic monitoring of tumor-inflamed microenvironment and immunotherapy response prediction

Journal for ImmunoTherapy of Cancer
We read with great interest the article by Bernatowicz et al. Despite the promising findings, we would like to highlight several concerns regarding the methodology and interpretation of the results that warrant further discussion, including the stability
Shuixing Zhang, Yuhao Dong
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Telomere variant sequences encode the genetic blueprint for allele-specific telomere length

Nature Communications
The ends of human chromosomes are capped by specialized nucleoprotein structures, termed telomeres, which are essential for genome stability. Recent advances in long-read sequencing have enabled allele-specific telomere length measurements at nucleotide ...
Xiaoran Chai, LaiFong Poon, Hengrui Liu, Manvendra K. Singh, Takashi Minami, Goro Sashida, Masafumi Fukuda, Bin Tean Teh, Patrick Tan, William Ying Khee Hwang, Jue Lin, Angela S. Koh, Tatsuro Kondoh, Lifeng Xu, Motomi Osato, Jin Liu, Shang Li   +16 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

The effects of sequencing strategies on Metagenomic pathogen detection using bronchoalveolar lavage fluid samples

Heliyon
Objectives: Metagenomic next-generation sequencing (mNGS) is a powerful tool for pathogen detection. The accuracy depends on both wet lab and dry lab procedures.
Ziyang Li, Zhe Guo, Weimin Wu, Li Tan, Qichen Long, Han Xia, Min Hu   +6 more
doaj   +1 more source