Results 91 to 100 of about 6,236,073 (332)
Upstream Open Reading Frames Differentially Regulate Gene-specific Translation in the Integrated Stress Response [PDF]
, 2016 Sara K. Young, Ronald C. Wek
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Writing to Read: Evidence for How Writing Can Improve Reading [PDF]
, 2010 Analyzes studies showing that writing about reading material enhances reading comprehension, writing instruction strengthens reading skills, and increased writing leads to improved reading.
core
Processing Advantages of Lexical Bundles: Evidence From Self‐Paced Reading and Sentence Recall Tasks [PDF]
, 2011 Antoine Tremblay +3 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Connecting Physical and Socio‐Economic Spaces for Multi‐Scale Urban Modelling: A Dataset for London
Geoscience Data JournalVersatile approaches for urban modelling need to simultaneously consider the physical characteristics of a city (urban form) and urban function as a manifestation of economically, socially, and culturally motivated human activities.
Denise Hertwig +7 more
doaj +1 more source
Metacognitive Reading Strategy Awareness of ESL and EFL Learners [PDF]
, 2004 Neil Anderson
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Meteorological ApplicationsThe urban heat island (UHI) effect exacerbates near‐surface air temperature (T) extremes in cities, with negative impacts for human health, building energy consumption and infrastructure.
Lewis P. Blunn +6 more
doaj +1 more source