Results 91 to 100 of about 1,487,886 (323)

EPIC: Efficient Privacy-Preserving Scheme with E2E Data Integrity and Authenticity for AMI Networks [PDF]

open access: yesarXiv, 2018
In Advanced Metering Infrastructure (AMI) networks, smart meters should send fine-grained power consumption readings to electric utilities to perform real-time monitoring and energy management. However, these readings can leak sensitive information about consumers' activities. Various privacy-preserving schemes for collecting fine-grained readings have
arxiv  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Machine learning bias correction and downscaling of urban heatwave temperature predictions from kilometre to hectometre scale

open access: yesMeteorological Applications
The urban heat island (UHI) effect exacerbates near‐surface air temperature (T) extremes in cities, with negative impacts for human health, building energy consumption and infrastructure.
Lewis P. Blunn   +6 more
doaj   +1 more source

Expectation-Maximization (EM) Algorithms for Mapping Short Reads Illustrated with FAIRE data and the TP53-WRAP53 Gene Region [PDF]

open access: yesarXiv, 2009
Huge numbers of short reads are being generated for mapping back to the genome to discover the frequency of transcripts, miRNAs, DNAase hypersensitive sites, FAIRE regions, nucleosome occupancy, etc. Since these reads are typically short (e.g., 36 base pairs) and since many eukaryotic genomes, including humans, have highly repetitive sequences then ...
arxiv  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Primary Hyperparathyroidism in Pregnancy: Successful Parathyroidectomy during First Trimester

open access: yesCase Reports in Endocrinology, 2018
Primary hyperparathyroidism in pregnancy can result in significant maternal and fetal complications. When indicated, prompt parathyroidectomy in the early second trimester is considered the treatment of choice.
Niranjan Tachamo   +5 more
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Hyperthyroidism with Biventricular Heart Failure and Cirrhotic Transformation of the Liver

open access: yesCase Reports in Cardiology, 2018
Cardiovascular symptoms remain the most common presenting features and leading causes of death in hyperthyroidism. We report a young female with reported thyroid disease and medication noncompliance presenting with atrial fibrillation, severe ...
Rashmi Dhital   +5 more
doaj   +1 more source

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