Results 101 to 110 of about 908,902 (242)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The Evolving Relationship Between Reading Motivation and Achievement: A Longitudinal Study

Education Sciences
This study examined the reciprocal relationship between reading engagement or motivation and reading achievement across primary and secondary grades in Chile. Using longitudinal SIMCE data from a cohort of 47,073 students assessed in Grade 4 (ages 9–10),
Montserrat Cubillos, Rodrigo Troncoso
doaj   +1 more source

Improving Students' Reading Comprehension through Student Team Achievement Division Technique

Loquen, 2017
This research was aimed at investigating the process of improving students’ reading comprehension through Student Team Achievement Division Technique and examining the effect of its implementation toward students’ abilities in reading comprehension. This
N. Erna Marlia Susfenti
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

THE CORRELATION BETWEEN STUDENTS’ MOTIVATION IN LEARNING ENGLISH AND THEIR ACHIEVEMENT IN READING COMPREHENSION AT THE FIRST GRADE STUDENTS OF MTS AT-TAQWA PASAWAHAN [PDF]

, 2012
TITI SUHARTI :THE CORRELATION BETWEEN STUDENTS ’ MOTIVATIONIN LEARNING ENGLISH AND THEIR ACHIEVEMENT IN READING COMPREHENSION AT THE FIRST GRADE STUDENTS OF MTS AT-TAQWA PASAWAHAN In communication, there are four skills of language namely, listening,
TITI SUHARTI,
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Improving Students' Achievement in Reading Comprehension Through Natural Approach [PDF]

, 2013
This study deals with improving stuudents' achievement in reading comprehension through natural approach. The objective of this study is to iinvestigate whether there is any significant improvement of the students' achievement in reading comprehension ...
Ginting, S. A. (Siti), Tinambunan, E. (Erbin)   +1 more
core  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

PENGARUH KAPASITAS INTELEGENSI MELALUI MENYIMAK DAN MEMBACA TERHADAP PRESTASI BELAJAR SISWA SMAN DI KOTA BANDUNG

Litera, 2016
This research study aims to investigate the direct effect of the intelligence capacity on learning achievement and the indirect effect of the intelligence capacity on learning achievement through listening and reading. This study employed the explanatory
pien supinah adiwiria
doaj