Results 61 to 70 of about 83,836 (307)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

THE EFFECTIVENESS OF MIND MAPPING TECHNIQUE IN ENHANCING STUDENTS’ READING ACHIEVEMENT

Lingua Didaktika: Jurnal Bahasa dan Pembelajaran Bahasa, 2019
Reading is considered challenging for high students in which students are not massively exposed to English input. Despite the challenge, the students are required to have good reading ability. One of the most proposing techniques is mind mapping.
Karolina Karolina
doaj   +1 more source

IMPROVING READING DESCRIPTIVE TEXT ACHIEVEMENT OF THE TENTH GRADE STUDENTS OF SMA NEGERI 10 PALEMBANG THROUGH THINK, PREDICT, READ, AND CONNECT (TPRC) STRATEGY

English Community Journal, 2020
This study aimed to find out whether or not there was (1) an improvement significant difference in students’ reading descriptive text achievement before and after they taught using TPRC Strategy, (2) a significant difference in reading descriptive text ...
Ulfatin Nur Rahmah, Bambang A Loeneto, Rita Inderawati   +2 more
doaj   +1 more source

An Elaboration on the Effect of Reading Anxiety on Reading Achievement

English Language Teaching, 2015
The presentstudy was an elaboration on the effect of foreign language anxiety on reading comprehension achievement of Iranian EFL learners. The participants comprised 100 BA students, doing General English Course in different academic fields at Islamic University of Neyshabur.
Bijan Mohammadpur, Narjes Ghafournia
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Kindergarten Instruction and early reading achievement [PDF]

, 1985
The relationship of the amount of classroom time devoted to reading instruction, the number of reading related activities, and teacher instruction feedback to reading achievement at the end of kindergarten was investigated for a sample of approximately ...
Linn, Robert L., Meyer, Linda A.
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Cognitive flexibility predicts early reading skills [PDF]

, 2014
An important aspect of learning to read is efficiency in accessing different kinds of linguistic information (orthographic, phonological, and semantic) about written words.
Blaye, Agnès, Colé, Pascale, Agnès eBlaye, Pascale eColé, Agnès Blaye, Pascale Colé, Duncan, Lynne G.; id_orcid, Duncan, Lynne G., Lynne G. Duncan   +8 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Measuring progress in reading achievement between primary and secondary school across countries [PDF]

This paper discusses a method to compare progress in reading achievement from primary to secondary school across countries. The method is similar to value-added models that take into account intake levels when comparing student progress in different ...
Maciej Jakubowski, Artur Pokropek
core