Results 61 to 70 of about 54,763 (259)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

GENDER DIFFERENCES IN READING COMPREHENSION ACHIEVEMENT (A CASE STUDY AT IAIN SYEKH NURJATI CIREBON)

open access: yesELT Echo: The Journal of English Language Teaching in Foreign Language Context, 2016
Language and gender have become a comprehensive issue in language learning. One aspect that is highlighted in language and gender is reading skill. The term of gender plays different perfomance and achievement in reading comprehension.
Jefy Fauzan
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Applying PQ4R Strategy for Teaching Reading

open access: yesIndonesian EFL Journal: Journal of ELT, Linguistics, and Literature, 2015
Despite receiving more attention than other language skills in English classroom, the result of students’ reading comprehension achievement is still far from expectation.
Moh.Rodli
doaj   +2 more sources

The Effect of Collaborative Strategic Reading on Grade Six Students’ Reading Achievement

open access: yesIJEE (Indonesian Journal of English Education), 2016
One of the language skills to master by Indonesian EFL learners is reading. In order to assist learners comprehend reading texts, teachers are challenged to apply various teaching strategies.
Siti Tamah
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

COVID-19 Pandemic and Student Reading Achievement – Findings from a School Panel Study [PDF]

open access: yesFront Psychol, 2022
Ludewig U   +7 more
europepmc   +2 more sources

Impact of Students’ Reading Preferences on Reading Achievement

open access: yesCreative Education, 2013
The reading preferences of 13-year-old boys and girls were examined to identify the factors determining reading achievement. Students from each Canadian province and one territory (N = 20,094) completed a questionnaire on, among others, the types of in-class reading activities.
Yamina Bouchamma   +3 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy