Results 101 to 110 of about 133,410 (293)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The relationship between working memory and reading comprehension in L1 Arabic and L2 English for Arabic speaking children

open access: yes, 2015
This mixed methodology research project comprised four studies that explored relationships between working memory and literacy, as well as the potential influence of home literacy, in L1 Arabic and L2 English children in grade six (aged 11) of mainstream
Elsayyad, H.M
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Syntactic awareness and reading ability: is there any evidence for a special relationship? [PDF]

open access: yes, 2007
Syntactic awareness has been linked to word reading and reading comprehension (Tunmer & Bowey, 1984). The predictive power of two syntactic awareness tasks (grammatical correction, word-order correction) for both aspects of reading was explored in eight-
Cain, Kate
core  

Answering the questions of “which, how, and when”: A comprehensive investigation of the relation between syntactic skills and reading comprehension

open access: yes, 2023
Reading comprehension, or the understanding of written texts, is a vital skill for full engagement in school and society, and, as such, is among the most important skills children learn in elementary school.
MacKay, Elizabeth
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The Effects of using Think-Pair-Share during Guided Reading Lessons

open access: yes, 2007
The aim of this research was to describe the effects of Think-Pair-Share strategies, used during Guided Reading lessons, on reading achievement. Think-Pair-Share is a co-operative teaching strategy that includes three components; time for thinking, time
Carss, Wendy Diane, Wendy Diane Carss
core  

The effects of a multicomponent reading intervention and a no treatment comparison on the reading comprehension of adolescent students who are adequate word readers and low in reading comprehension [PDF]

open access: yes, 2013
textThis experimental study was conducted to examine the effectiveness of multicomponent reading intervention and a no treatment comparison condition on the reading comprehension of adolescent students with adequate word reading and low reading ...
Solis, Michael R.
core  

The Relationship Between Morphological Awareness and Reading Comprehension Among Chinese Children

open access: yesFrontiers in Psychology, 2019
The present study examined the developmental relationship between morphological awareness and reading comprehension, using a 1-year longitudinal study with a sample of 439 Chinese-speaking students in Grades 1, 3, and 5, respectively.
Ruibo Xie   +3 more
doaj   +1 more source

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