Results 71 to 80 of about 1,358,252 (280)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Tracking Eye Movements in Sight Translation – the comprehension process in interpreting [PDF]

open access: yes, 2011
[[abstract]]While the three components of interpreting have been identified as comprehension, reformulation, and production, the process of how these components occur has remained relatively unexplored.
黃致潔
core  

Investigating the Relationship Between Oral Reading Miscues and Comprehension in L2 Chinese

open access: yesLanguages
Reading comprehension in Chinese as a second language (L2 Chinese) presents unique challenges due to the language’s logographic writing system. Analysis of oral reading miscues reveals specific patterns in L2 learners’ reading processes and comprehension
Sicheng Wang
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The role of cognates in reading comprehension: a cognitive perspective [PDF]

open access: yes, 2003
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em Letras/Inglês e Literatura Correspondente.Research on cognates has strongly indicated that there is a close relationship ...
Souza, Vilmar Ferreira de
core  

Evaluating the Simple View of Reading Model: Longitudinal Testing and Applicability to the Swedish Language

open access: yesEducation Sciences
This study investigates the empirical validity of the simple view of reading model in a semi-transparent language, Swedish, by using a large amount of reading test data from 11,791 students. Data were collected during the primary grades (year 1–3), which
Thomas Nordström   +2 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

The Effects of using Think-Pair-Share during Guided Reading Lessons [PDF]

open access: yes, 2007
The aim of this research was to describe the effects of Think-Pair-Share strategies, used during Guided Reading lessons, on reading achievement. Think-Pair-Share is a co-operative teaching strategy that includes three components; time for thinking, time
Carss, Wendy Diane, Wendy Diane Carss
core  

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