Results 41 to 50 of about 512,859 (300)
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Brain Sciences, 2022 This study examined the comprehension of passive sentences in order to investigate whether individuals with dyslexia rely on parsing heuristics in language comprehension to a greater extent than non-dyslexic readers.
Marianna Stella, Paul E. Engelhardt
doaj +1 more source
Developmental dyslexia: specific phonological deficit or general sensorimotor dysfunction? [PDF]
, 2003 Dyslexia research is now facing an intriguing paradox: it is becoming increasingly clear that a significant proportion of dyslexics present sensory and motor deficits; however, as this “sensorimotor syndrome” is being studied in greater detail, it is ...
Ramus, Dr Franck
core
Development of reading comprehension with graphic organizers for students with dyslexia [PDF]
, 2018 This academic work has the aim of analyzing the impact of graphic organizers in the development of reading comprehension accordance with the level of English of each student. The theoretical foundation is constructed by the contents previously defined in
Campoverde, Johnny, Lopez, Jacqueline
core +3 more sources
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Education SciencesDyslexia is a highly prevalent learning disability characterized by deficits in specific cognitive and linguistic skills which impair accurate and fluent reading of written words.
Anna E. Middleton +5 more
doaj +1 more source
Benign Rolandic Epilepsy and Learning Disabilities
Pediatric Neurology Briefs, 2009 Neuropsychological impairments in 35 children with rolandic epilepsy, and the relationship to electroencephalographic findings, were studied at Ege University, Izmir, Turkey.
J Gordon Millichap
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source