Results 71 to 80 of about 312,214 (306)

Single‐Cell Metabolic Imaging and Digital Scoring of Fat Tissue Remodeling by Label‐Free Metabolic Microscopy

open access: yesAdvanced Science, EarlyView.
Mid‐infrared optoacoustic microscopy (MiROM) acquires lipid‐ and protein‐ associated vibrational contrast in intact fat tissue without dyes, preserving native tissue architecture. Through lateral and axial segmentation, MiROM tracks intrinsic intracellular changes during postnatal remodeling. A quantitative spatial analysis tool (Q‐SAT) maps white‐ and
Myeongseop Kim   +7 more
wiley   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

open access: yesAdvanced Science, EarlyView.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin   +12 more
wiley   +1 more source

Helix Alignment, Chevrons, and Edge Dislocations in Twist‐Bend Ferroelectric Nematics

open access: yesAdvanced Science, EarlyView.
The recently discovered twist‐bend ferroelectric nematic (NTBF) is the new member of the multiferroic family, representing a fluid with an oblique helicoidal (heliconical) periodic structure of spontaneous electric polarization. The work presents a thorough exploration of the material properties of this phase, how the periodic modulation of ...
Bijaya Basnet   +8 more
wiley   +1 more source

THE ROLE OF LEXICAL FREQUENCY IN MODERATING THE EFFECT OF GRAMMAR KNOWLEDGE ON L2 READING OUTCOMES

open access: yesTEFLIN Journal, 2018
Sentence-level grammar skills are of the important foundations in the mastery of reading skills in second language (L2). Previous studies showed inconclusive findings about the effect of grammar knowledge on L2 reading.
Sahiruddin Sahiruddin
doaj   +1 more source

Eye Movement Patterns in Natural Reading: A Comparison of Monolingual and Bilingual Reading of a Novel. [PDF]

open access: yesPLoS ONE, 2015
This paper presents a corpus of sentence level eye movement parameters for unbalanced bilingual first language (L1) and second-language (L2) reading and monolingual reading of a complete novel (56 000 words). We present important sentence-level basic eye
Uschi Cop, Denis Drieghe, Wouter Duyck
doaj   +1 more source

A Methodological Synthesis of Self-Paced Reading in Second Language Research:Methodological synthesis of SPR tests [PDF]

open access: yes, 2018
Self-paced reading tests (SPRs) are being increasingly adopted by second language (L2) researchers. Using SPR with L2 populations presents specific challenges, and its use is still evolving in L2 research (as well as in first language research, in many ...
Marsden, Emma Josephine   +2 more
core   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

The effects of a reading intervention on first and second language English medium learners. [PDF]

open access: yes, 2012
Due to the detrimental effects of apartheid on the South African learning environment the implementation of language policies aimed at fostering multilingual and multicultural education to attain educational equity are rendered impractical (DoE, 1995; de
Carter, Kirsty
core  

Using keystroke logging to understand writers’ processes on a reading-into-writing test [PDF]

open access: yes, 2017
Background Integrated reading-into-writing tasks are increasingly used in large-scale language proficiency tests. Such tasks are said to possess higher authenticity as they reflect real-life writing conditions better than independent, writing-only tasks.
A Cumming   +38 more
core   +2 more sources

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