Results 81 to 90 of about 312,214 (306)

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

First and Second Language Use in Reading Comprehension Strategies of Japanese ESL Students [PDF]

, 1997
This article submitted to IUPUI ScholarWorks as part of the OASIS Project. Article reproduced with permission of the copyright owner. Further reproduction prohibited without permission.
Upton, Thomas A. (Thomas Albin)
core  

An fMRI study on the processing of long-distance wh-movement in a second language [PDF]

, 2017
Recent behavioural evidence from second language (L2) learners has suggested native-like processing of syntactic structures, such as long-distance wh-dependencies in L2. The underlying processes are still largely debated, while the available neuroimaging
Beckmann, Ben-Shachar, Ben-Shachar, Bonhage, Caplan, Chomsky, Chomsky, Chomsky, Chomsky, Clahsen, Clifton, Cooke, Cunnings, Dallas, De Grauwe, Dekydtspotter, Dussias, Felser, Felser, Fiebach, Frazier, Friederici, Friederici, Friston, Geranpayeh, Gibson, Gibson, Hagoort, Hahne, Hasegawa, Hopp, Hopp, Indefrey, Jackson, Just, Kaan, Kluender, Makuuchi, Marinis, McDonald, Omaki, Parker Jones, Piñango, Pliatsikas, Pliatsikas, Pliatsikas, Pliatsikas, Richlan, Roberts, Rüschemeyer, Rüschemeyer, Santi, Santi, Santi, Santi, Schneider, Schneider, Smith, Stowe, Suh, Woolrich, Woolrich   +61 more
core   +2 more sources

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

L2 Reading Assessment from a Sociocultural Theory Perspective: The Contributions of Dynamic Assessment

Education Sciences
Our understanding of assessing L2 reading has significantly expanded in recent years, including both theoretical and practical aspects. There is a growing consensus that reading comprehension involves multiple skills and subskills.
Ali Kushki, Hossein Nassaji
doaj   +1 more source

Facebook activities and the investment of L2 learners [PDF]

, 2016
The article discusses the investment of L2 learners in the English language on Facebook that they portrayed through their Facebook activities. It studied four informants consisted of diploma students in a Malaysian university.The study consisted of 14 ...
Karpal Singh, Paramjit Kaur, Shafie, Latisha Asmaak, Yaacob, Aizan   +2 more
core   +1 more source

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

Advanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong, James Trevarthen, Igor Dolbnya, Wadwan Singhapong, Nicholas Pilato, Richard Butler, Jiraphant Srisuriyachot, Alexander J. G. Lunt   +7 more
wiley   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Effects of Task Complexity on L2 Reading and L2 Learning

English Teaching, 2016
Task-based language teaching (TBLT) has propelled much research into how task type, condition, or demand affects L2 learners’ linguistic performance...
openaire   +1 more source