Results 91 to 100 of about 130,524 (289)
Reading in a foreign language: Strategic variation between readers of differing proficiency [PDF]
, 2002 For university language students who are required to deal with literary texts for linguistic or literary purposes, there is hardly any transitional stage between short adapted expository texts, read in the early stages of language learning, and complex
Bouvet, Eric James
core
No Lords A-Leaping: Fanon, C.L.R. James, and the Politics of Invention
Humanities, 2014 What happens to Fanonism when, instead of resistance or liberation, it becomes a discourse of invention? What happens to Fanon’s critique of colonialism and his imagining of a decolonial future, when that critique and imagining are staked not on the ...
David Marriott
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Reading Riddles Rhetorics of Obscurity from Romanticism to Freud [PDF]
Reading Riddles: Rhetorics of Obscurity from Romanticism to Freud explores how the riddle becomes a figure for reading and writing in early German Romanticism and how this model then enables Sigmund Freud's approach to the psyche.
Tucker, Brian.
core
Lack of semantic parafoveal preview benefit in reading revisited [PDF]
, 2014 In contrast to earlier research, evidence for semantic preview benefit in reading has been reported by Hohenstein and Kliegl (Experimental Psychology: Learning, Memory, and Cognition, 40, 166–190, 2013) in an alphabetic writing system; they also implied ...
Schotter, Elizabeth R. +2 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
The impact of guided doodle note-taking on reading comprehension
Discover EducationThe purpose of this quasi-experimental non-equivalent control-group study is to determine the impact of guided doodle note-taking strategies on middle school students’ perceived reading comprehension, compared by gender and whole group. The importance of
Kayla DeWald, R. M. Lunde
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source