Results 111 to 120 of about 130,524 (289)

The Effects of a Shared Reading Intervention on the English Reading Skills of Year One Students in a Level Two Māori-medium Educational Context [PDF]

open access: yes, 2014
One of the biggest challenges confronting literacy education in Aotearoa New Zealand is accommodating the differences in English reading-related variables at school entry to produce equitable outcomes in later reading achievement (Wilkinson, Freebody, &
Te Arihi, Kylie
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Reading the article of L.Gudkov: Marginal notes [PDF]

open access: yesСоциологический журнал, 2010
Russian sociologists are actively involved in the debate over epistemological foundations of social science. The commentary underlines that sociology was born in the West, Russian sociology in the initial phase of its development had to borrow ideas from
doaj  

Cum putem citi însemnările neînsemnate [PDF]

open access: yesRevista de Istorie și Teorie Literară, 2016
There was a custom in the 17th and 18th centuries for the readers of the old books to put down on the pages they were reading some notes about themselves or about the social, political and natural context they were living in.
Cristina Ioana Dima
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Developing a reading programme through an action research in a secondary school [PDF]

open access: yes, 2006
The purpose of this study is to identify factors that could promote interest and motivation in reading among the non readers as part of Ping Yi Secondary School Media Resource Library's activities.
Bibi Jan Mohd Ayyub,   +1 more
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Notes From The Reading Daily Times, 1858-1859 [PDF]

open access: yes, 1950
A set of handwritten notes copied from The Reading Daily Times, transcribed by Alfred L. Shoemaker circa 1950. The notes cover topics including humorous ballads, an old turtle, and the death of a Wurst Frau.https://digitalcommons.ursinus.edu ...
Shoemaker, Alfred L.
core   +1 more source

Reflexões sobre o aprendizado formal em Humanidades com base no projeto “Práticas de leitura e escrita acadêmicas”

open access: yesEstudos Avançados
Resumo O artigo apresenta o histórico e as principais características de uma disciplina de graduação com estrutura interdisciplinar - Práticas de leitura e escrita acadêmicas -, cujo projeto foi elaborado em 2014, vem sendo desenvolvido e ampliado na ...
Marcus Sacrini, Valéria De Marco
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

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