Results 121 to 130 of about 130,524 (289)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
" I Am in Grade One and I Can Read!" The Readers' Workshop [PDF]
, 2015 This study analyzed the effects of the implementation of the readers' workshop on students' reading levels and comprehension skills in a first-grade, mixed-ability classroom in Lebanon.
Nabhani, Mona +2 more
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Enhancing the Reading Engagement of University English Language Learners: An Action Research Project [PDF]
, 2015 Despite burgeoning research that has been conducted on the broad term “engagement” in the past decades, research into engagement in English as a Second Language (ESL) or English as a Foreign Language (EFL) contexts remains scarce.
Lee, Jocelyn Yee Vun
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
LANGUAGE-Reading notes on Chinese Grammar [PDF]
Electronic reproduction from Rulan Chao Pian Manuscript ...
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An examination of the relationship between reading and drama in education. [PDF]
, 1978 The purpose of this thesis was to examine the theories of drama In education and of developmental reading in order to determine the relationship between drama and reading in the cognitive and affective development of children and to document that ...
Booth, David Wallace
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Articles & Reading Notes on P.O.-Untitled folder [PDF]
Electronic reproduction from Rulan Chao Pian Manuscript ...
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source