Results 91 to 100 of about 808,683 (307)
On measuring the impact of hyperlinks on reading [PDF]
, 2013 We increasingly spend a vast amount of time on the Web and much of that time is spent reading. One of the main differences between reading non-Web based text and reading on the Web is the presence of hyperlinks within the text, linking various related ...
Fitzsimmons, Gemma +5 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
AlephOn the timeline of the development of reading, the real revolution was marked by the rise of structural cognitivism in the 1970s, anticipating another breakthrough that would result from artificial intelligence.
Abdelhalim Melzi
doaj
Capturing reading strategies in young children
, 2011 Traditional models of children’s reading, based on fixed invariant stages, have proved less than adequate in explaining the flexibility in which children approach the task of learning to read.
Coyne, EJ
core
Tracking Eye Movements in Sight Translation – the comprehension process in interpreting [PDF]
, 2011 [[abstract]]While the three components of interpreting have been identified as comprehension, reformulation, and production, the process of how these components occur has remained relatively unexplored.
黃致潔
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Reading in a foreign language: Strategic variation between readers of differing proficiency [PDF]
, 2002 For university language students who are required to deal with literary texts for linguistic or literary purposes, there is hardly any transitional stage between short adapted expository texts, read in the early stages of language learning, and complex
Bouvet, Eric James
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source