Results 71 to 80 of about 3,645,445 (303)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Improving reading: a handbook for improving reading in key stages 3 and 4 (National Strategies: secondary) [PDF]
, 2009 "This handbook explores what it means to be a reader and some core challenges and skills that need to be addressed in the teaching of reading. The handbook outlines a route to improvement that can be followed to ensure that all pupils make expected ...
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Journal of Language and Education, 2018 Although IELTS is coordinated under a framework for test development and validation, there is some controversy about exam results’ correlation with students’ post-admission intellectual, academic and professional performance.
Marina Kovalenko
doaj +1 more source
The social construction of meaning : Reading Animal Farm in the classroom [PDF]
, 2013 The novel, it has generally been assumed, was from its very beginnings a literary form designed to be read by solitary, silent individuals. One consequence of this assumption is that the class novel, read amid all the noise and sociality of the classroom,
Yandell, John
core +1 more source
Observing professionals taking notes on screen [PDF]
, 2005 In this study 38 participants wrote a piece of advice based on reading and annotating information from an extensive Web site. Half of the participants took notes in a separate window, the other half used an advanced annotation tool.
Melenhorst, Mark
core +3 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Optimal line length for reading schoolbook on screen [PDF]
, 2013 Although experimental studies have shown a strong impact of text layout on the legibility of e- text, many digital texts appearing in eBook or the internet use different designs, so that there is no straightforward answer in the literature over which one
Abubaker, Azza, Lu, Joan
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Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Developing Students’ Reading Culture for Academic Reading Level through Metacognitive Strategies
Lingua Cultura, 2018 The development of reading culture for this academic level used the metacognitive strategies. This research was a case study in wihich the data sources were randomly drawn from various print sources by cutting off the core of the text to be analyzed. The
Pranowo pranowo
doaj +3 more sources