Results 61 to 70 of about 3,645,445 (303)

Exploration and Exploitation of Victorian Science in Darwin's Reading Notebooks [PDF]

open access: yes, 2016
Search in an environment with an uncertain distribution of resources involves a trade-off between exploitation of past discoveries and further exploration. This extends to information foraging, where a knowledge-seeker shifts between reading in depth and
Akaike   +60 more
core   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Switching between reading tasks leads to phase-transitions in reading times in L1 and L2 readers.

open access: yesPLoS ONE, 2019
Reading research uses different tasks to investigate different levels of the reading process, such as word recognition, syntactic parsing, or semantic integration.
Sebastian Wallot   +2 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Miscue analysis: A glimpse into the reading process

open access: yesStudies in English Language and Education, 2018
This paper aims to analyse Form One students’ ability in reading prose. A qualitative research method was carried out involving 6 average ability students.
Che Ton binti Mahmud, Revathi Gopal
doaj   +1 more source

High speed spatially multimode atomic memory

open access: yes, 2011
We study the coherent storage and retrieval of a very short multimode light pulse in an atomic ensemble. We consider a quantum memory process based on the conversion of a signal pulse into a long-lived spin coherence via light matter interaction in an on-
Bramati, A.   +5 more
core   +1 more source

Introduction : Viewing animals [PDF]

open access: yes, 2005
The introduction to this special issue of Worldviews goes back to the first European encounters with the New World as a way of opening up a discussion about the nature of viewing animals.
Fudge, Erica
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

MENGEMBANGKAN BUDAYA BACA TULIS SEBAGAI PROSES MEMBENTUK KARAKTER

open access: yesJurnal Pustaka Ilmiah, 2019
A strong correlation exists between reading ability and writing ability. Reading is the window of the world. To produce quality writing then requires the process of internalization of knowledge by reading.
Endang Fatmawati
doaj   +1 more source

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