Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Eye-Tracking-Based Interventions for School-Age Specific Learning Disorders: A Narrative Review of Functional Assessment and Gaze-Contingent Training. [PDF]
Diotaiuti P +5 more
europepmc +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
Pay It Forward: Analysis of a novel peer-to-peer support initiative for individuals receiving treatment for head and neck cancer. [PDF]
Mason M +5 more
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Enhancing EFL reading proficiency through mediated learning: Impacts on cognitive and metacognitive strategies. [PDF]
Bezabih S +4 more
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Binocular Reading Speed Comparison: Patients After Bilateral Trifocal IOL Implantation versus Those without Cataract -A Prospective, Dual-Center Study. [PDF]
Lin Y +7 more
europepmc +1 more source
Metacognitive strategy use in GenAI-supported academic reading: a qualitative study of postgraduate students in UK higher education. [PDF]
Dai Y.
europepmc +1 more source
An empirical analysis of the impact of early educational interventions before age three on cognitive development. [PDF]
Yi K, Xiong W, Ou JJ.
europepmc +1 more source

