Results 91 to 100 of about 1,891,496 (337)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

READING STRATEGIES IN EFL CLASSROOM: A THEORETICAL REVIEW

open access: yesCendekia: Jurnal Pendidikan dan Pembelajaran, 2014
Teaching reading has been long discussed in the context of English teaching curriculum in Indonesia.  The ground of English curriculum (e.g. 1984, 1994, 2004 English curriculum) lays reading as the main model of teaching English in the secondary school ...
Teguh Budiharso
doaj   +1 more source

KWL and Homer\u27s Illiad. [PDF]

open access: yes, 2013
As a student teacher I was disappointed at initial confusion by my World Literature students when we began reading Homer’s Iliad. I wanted to probe my students about the fascinating questions the story raises about the Greek culture, the qualities of a ...
Menke, Kristen
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Rhetorical Reading for Writing Strategies [PDF]

open access: yesJournal of ELT Research, 2019
This article is based on the plenary talk given at the inaugural UHAMKA International Conference on English Language Teaching (ELT) and Computer Assisted Language Learning (CALL) (UICELL 2018) in Jakarta, Indonesia, 23 November 2018, and focuses on the explanation of reading as a communicative rhetorical act. Outlining the key features of such reading,
openaire   +4 more sources

Analysis of ESP university students' reading strategy awareness [PDF]

open access: yes, 2008
The research literature on metacognitive awareness of reading strategies indicates the need to increase our understanding of readers’ metacognitive knowledge about reading and reading strategies so that individuals develop into active, constructively ...
Lahuerta Martínez, Ana Cristina
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

TECHNIQUES OF TEACHING READING SKILL ON THE SECOND YEAR STUDENTS AT SMK PGRI 3 MADIUN [PDF]

open access: yes, 2005
This study is a research that concerns with the techniques of teaching reading skill. The researcher conducts this study because she observes that English teaching in education field is not as purposed nowadays.
DEWI MARSITOH, NURUL
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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