Results 111 to 120 of about 1,934,051 (281)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Computer-based programs on acquisition of reading skills in schoolchildren (review of contemporary foreign investigations) [PDF]
Современная зарубежная психология, 2015 The article presents a description of 17 computer-based programs, which were used over the last 5 years (2008—2013) in 15 studies of computer-assisted reading instruction and intervention of schoolchildren.
Prikhoda N.A.
doaj
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
BidayatunaThe purpose of this study was to compare the effectiveness of using reading aloud and sustained silent reading strategies on the ability to explain reading content in terms of the opinions/perceptions of high-grade students.
M. Habibie, Lasti Rahma Winta
doaj +1 more source
Literary reading: interactive methods and techniques [PDF]
Формування читацької компетентності молодших школярів, яка є індивідуальним інтегрованим утворенням, передбачає різні види завдань на перечитування, розуміння, відтворення і зміни текстів, залежно від мети опрацювання, їх жанру, обсягу, складності.
Савченко, Олександра Яківна
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Vision and Reading Difficulties Part 5: Clinical protocol and the role of the eye-care practitioner [PDF]
, 2009 This series of articles has described various aspects of visual characteristics of reading difficulties and the background behind techniques such as the use of coloured filters in helping to reduce the difficulties that are experienced.
Allen, Peter M +2 more
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Education SciencesThe Sustainable Development Goals Report 2024, published by the United Nations, highlights quality education as a priority goal, emphasising its essential role in facilitating the achievement of other goals.
Inga Linde, Linda Daniela
doaj +1 more source