Results 131 to 140 of about 12,504 (200)

Regulatory Mechanisms and Functional Roles of Readthrough Transcripts in Tumorigenesis. [PDF]

Int J Mol Sci
Modestov A, Zakharova G, Poddubskaya E, Buzdin A.   +3 more
europepmc   +1 more source

Beyond the stop: Oxadiazole TRIDs restore LRBA protein expression in nonsense-driven primary immunodeficiency. [PDF]

Mol Ther Nucleic Acids
Fiduccia I, Vitale E, Varrica R, Ricci D, Marino S, Zito A, Pace A, Colige A, Moutschen M, Borutzki Y, Bileck A, Meier-Menches SM, Lentini L, Pibiri I.   +13 more
europepmc   +1 more source

Ribosomal read through as an alternative therapy for patients with hemophilia with nonsense mutations. [PDF]

J Thromb Haemost
Liu Z, Srivastava V, Hussain A, Zhang B.
europepmc   +1 more source

AAV-delivered engineered suppressor tRNA rescues visual function in mice with an inherited retinal disease. [PDF]

Nat Commun
Ren C, Song L, Hu M, Jin X, Liang L, Liu F, Su J, Fu J, Yang Y, Liu M, Xu Q, Wu X, Luo M, Ye Q, Li Q, An Y, Li M, She K, Wei Y, Lu F, Yang Y.   +20 more
europepmc   +1 more source

Mechanism of ribosome stalling by the AMD1 C-terminal tail arrest peptide. [PDF]

Sci Adv
Maldosevic E, Boiocchi FS, Swirski MI, Meiklejohn KA, Yordanova MM, Baranov PV, Jomaa A.   +6 more
europepmc   +1 more source

Beyond readthrough: ataluren restores mitochondrial function and reduces oxidative stress in FANCA-mutated cells via mTOR-DRP1 modulation. [PDF]

Cell Death Discov
Balbi M, Guidi E, Hristodor AM, Corsolini F, Cossu V, Bottega R, Serra M, Pestarino S, Bartolucci M, Cipolli M, Regis S, Bezzerri V, Cappelli E, Ravera S.   +13 more
europepmc   +1 more source

mRNA-based immunotherapy platform targeting endometrial cancer. [PDF]

J Transl Med
Freyberg M, Dierks M, Nass N, George C, Geffken M, Ignatov A, Kalinski T, Ignatova Z.   +7 more
europepmc   +1 more source

Prime editing-installed suppressor tRNAs for disease-agnostic genome editing. [PDF]

Nature
Pierce SE, Erwood S, Oye K, An M, Krasnow N, Zhang E, Raguram A, Seelig D, Osborn MJ, Liu DR.   +9 more
europepmc   +1 more source

Transcription termination counteracts DNA damage after WEE1 inhibition. [PDF]

Nucleic Acids Res
Landsverk HB, Sandquist LE, Bay LTE, Hauge S, van Bijsterveldt L, Lindbergsengen L, Lund-Andersen C, Kanduri C, Lyng H, Fjeldbo CS, Hompland T, Humphrey TC, Syljuåsen RG.   +12 more
europepmc   +1 more source

CFTR rescue in W1282X cystic fibrosis patient-derived intestinal organoids (PDIOs) mediated by translational readthrough-inducing drugs (TRIDs). [PDF]

Genet Med Open
Perriera R, Ramalho AS, Vermeulen F, Vitale E, Pibiri I, Pace A, Lentini L.   +6 more
europepmc   +1 more source