Results 111 to 120 of about 12,504 (200)

Misincorporations of amino acids in p53 in human cells at artificially constructed termination codons in the presence of the aminoglycoside Gentamicin

Frontiers in Genetics
Readthrough of a translation termination codon is regulated by ribosomal A site recognition and insertion of near-cognate tRNAs. Small molecules exist that mediate incorporation of amino acids at the stop codon and production of full-length, often ...
Kamila Pawlicka, Tomas Henek, Lukas Uhrik, Lenka Hernychova, Monikaben Padariya, Jakub Faktor, Sławomir Makowiec, Borivoj Vojtesek, Borivoj Vojtesek, David Goodlett, Ted Hupp, Ted Hupp, Umesh Kalathiya   +12 more
doaj   +1 more source

Correction: Functional Translational Readthrough: A Systems Biology Perspective

PLOS Genetics, 2016
[This corrects the article DOI: 10.1371/journal.pgen.1006196.].
openaire   +3 more sources

PTC readthrough [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

Translational error in mice increases with ageing in an organ-dependent manner

Nature Communications
The accuracy of protein synthesis and its relation to ageing has been of long-standing interest. To study whether spontaneous changes in the rate of ribosomal error occur as a function of age, we first determined that stop-codon readthrough is a more ...
Erik C. Böttger, Harshitha Santhosh Kumar, Adrian Steiner, Emmanuel Sotirakis, Kader Thiam, Patricia Isnard Petit, Petra Seebeck, David P. Wolfer, Dimitri Shcherbakov, Rashid Akbergenov   +9 more
doaj   +1 more source

Programmed Translational Readthrough in Drosophila melanogaster [PDF]

, 2022
openaire   +2 more sources

Transcriptional readthrough precedes alternative splicing programs triggered in CML cells by imatinib. [PDF]

Sci Adv
Podszywałow-Bartnicka P, Shine M, Lin J, Neugebauer KM.   +3 more
europepmc   +1 more source

Identification of small molecules that enhance aminoglycoside-mediated suppression of <i>CFTR</i> and <i>NF1</i> nonsense mutations. [PDF]

Mol Ther Oncol
Sammons J, Chen J, Thrasher K, Fu L, Du M, Wen H, Bostwick JR, Vinson P, Moukha-Chafiq O, Augelli-Szafran C, Keeling KM, Wallis D, Kesterson RA, Rowe SM, Bedwell DM.   +14 more
europepmc   +1 more source

A Translational Roadmap for Neurological Nonsense Mutation Disorders. [PDF]

Int J Mol Sci
Li J, Zhu Z, Xu S.
europepmc   +1 more source

Turning premature stop codons into therapeutic opportunities. [PDF]

Mol Ther Nucleic Acids
Williamson J, Jacków-Malinowska J.
europepmc   +1 more source

Frequent occurrence and predicted functions of tRNAs with 4-base-pair anticodon stems in bacteria: extended superwobble hypothesis. [PDF]

Nucleic Acids Res
Fakih F, Nandipati S, Kachale A, Heller J, Žváček J, Brázdovič F, Al-Chamy N, Tripathi P, Paris Z, Valášek LS, Kolář MH, Yurchenko V, Eliáš M, Koonin EV, Lukeš J, Butenko A.   +15 more
europepmc   +1 more source