Results 71 to 80 of about 1,738,958 (224)

Asymptotic Bayesian Decision Feedback Equalizer Using a Set of Hyperplanes

open access: yes, 2000
We present a signal space partitioning technique for realizing the optimal Bayesian decision feedback equalizer (DFE). It is known that, when the signal to noise ratio (SNR) tends to infinity, the decision boundary of the Bayesian DFE is asymptotically ...
Mulgrew, B., Hanzo, L., Chen, S.
core  

Approximation of Univariate Set-Valued Functions - an Overview [PDF]

open access: yes, 2007
2000 Mathematics Subject Classification: 26E25, 41A35, 41A36, 47H04, 54C65.The paper is an updated survey of our work on the approximation of univariate set-valued functions by samples-based linear approximation operators, beyond the results reported in ...
Dyn, Nira, Mokhov, Alona, Farkhi, Elza
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Manifold approximation of set-valued functions

open access: yes, 2005
A new continuity for set-valued functions is introduced, and an existence theorem is proved for such continuous set-valued ...
Goldsztejn, Alexandre
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Fixed point for derivative and differentiation of single-valued and set-valued functions on metric spaces [PDF]

open access: yes, 2019
Study of the fixed point for derivative functions is an effort to expand the knowledge of fixed point for functions. This study represents original research on the existence of the fixed point for derivative functions which has been not studied before.
Muslikh, Mohamad
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

A Characterization Theorem for Aumann Integrals

open access: yes, 2014
A Daniell-Stone type characterization theorem for Aumann integrals of set-valued measurable functions will be proven. It is assumed that the values of these functions are closed convex upper sets, a structure that has been used in some recent ...
Rudloff, Birgit   +3 more
core   +1 more source

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