Results 101 to 110 of about 734,685 (383)

Detection of congenital cytomegalovirus infection by real-time polymerase chain reaction analysis of saliva or urine specimens.

Journal of Infectious Diseases, 2014
Viral culture of urine or saliva has been the gold standard technique for the diagnosis of congenital cytomegalovirus (CMV) infection. Results of rapid culture and polymerase chain reaction (PCR) analysis of urine and saliva specimens from 80 children ...
Shannon A. Ross, Amina Ahmed, A. Palmer, M. Michaels, P. Sánchez, D. Bernstein, R. Tolan, Zdeněk Novák, Nazma Chowdhury, K. Fowler, S. Boppana   +10 more
semanticscholar   +1 more source

Orchestrated increase of dopamine and PARK mRNAs but not miR-133b in dopamine neurons in Parkinson's disease [PDF]

, 2014
Progressive loss of substantia nigra dopamine neurons (SN DA) is a hallmark of aging and of Parkinson's disease (PD). Mutations in PARK genes cause familial PD forms.
Dragicevic, Elena, Fauler, Michael, Gründemann, Jan, Hardy, John, Liss, Birgit, Schlaudraff, Falk   +5 more
core   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

DNA extraction and polymerase chain reaction

Journal of Cytology, 2019
DNA extraction and polymerase chain reaction (PCR) are the basic techniques employed in the molecular laboratory. This short overview covers various physical and chemical methods used for DNA extraction so as to obtain a good-quality DNA in sufficient ...
Nalini Gupta
doaj   +1 more source

Detection of Typhoidal and Paratyphoidal Salmonella in Blood by Real-time Polymerase Chain Reaction.

Clinical Infectious Diseases, 2015
BACKGROUND The gold standard for diagnosis of enteric fever caused by Salmonella Typhi or Salmonella Paratyphi A or B is bone marrow culture. However, because bone marrow aspiration is highly invasive, many hospitals and large health centers perform ...
S. Tennant, D. Toema, F. Qamar, N. Iqbal, M. Boyd, Joanna M. Marshall, W. Blackwelder, Yukun Wu, Farheen Quadri, Asia Khan, F. Aziz, K. Ahmad, A. Kalam, E. Asif, S. Qureshi, E. Khan, A. Zaidi, M. Levine   +17 more
semanticscholar   +1 more source

Infrequent Replication of Parvovirus B19 and Erythrovirus Genotypes 2 and 3 among HIV-Infected Patients with Chronic Anemia [PDF]

, 2017
We investigated the role that erythroviruses (parvovirus B19 and erythrovirus genotypes 2 and 3) play in the lives of immunosuppressed HIV-infected patients with chronic anemia.
Bernasconi, Enos, Calmy, Alexandra, Dang, Thanh, Delhumeau, Cécile, Elzi, Luigia, Ferry, Tristan, Hirschel, Bernard, Meylan, Pascal, Rauch, Andri, Schmid, Patrick, Weber, Rainer   +10 more
core  

Interleukin-21 receptor might be a novel therapeutic target for the treatment of rheumatoid arthritis [PDF]

, 2014
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by the synovial inflammation of the joints. Various cells and cytokines have been identified that may contribute to RA pathology. Interleukin (IL)-21 is a proinflammatory
Andersson, Arnett, Asao, Bagheri, Bagheri, Boghozian, Boissier, Brandt, Carbone, Caruso, Christodoulou, Dolff, Fantini, Feldmann, Frleta, Fröhlich, Gabriel, Geri, Grebowska, Herber, Hong, Jang, Jüngel, Kiani, Korn, Lebre, Lee, Leonard, Leonard, Li, Li, Liu, Liu, McInnes, Monteleone, Monteleone, Niu, Nurieva, Nurieva, Parrish-Novak, Parrish-Novak, Sandoo, Singh, Son, Spolski, Strengell, Terrier, Van Belle, Vieira, Vollmer, Young   +50 more
core   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

A comparison of three diagnostic platforms for the detection of influenza A and B in children

Biomedical and Biotechnology Research Journal, 2018
Background: Viral flu is the predominant cause of hospitalization in young children, which invariably leads to enhanced morbidity and mortality in children in developing countries. Initial treatment of viral flu is based on presumptive diagnosis. Bedside
Furqan Kabir, Marvi Tariq, Fatima Aziz, Syed Imran Rizvi, Shahida Qureshi, Asad Ali, Najeeha Talat Iqbal   +6 more
doaj   +1 more source

qpcR: an R package for sigmoidal model selection in quantitative real-time polymerase chain reaction analysis

Bioinform., 2008
UNLABELLED The qpcR library is an add-on to the free R statistical environment performing sigmoidal model selection in real-time quantitative polymerase chain reaction (PCR) data analysis.
C. Ritz, A. Spiess
semanticscholar   +1 more source