Results 161 to 170 of about 731,111 (296)

Real-time polymerase chain reaction (PCR) for <i>Pneumocystis jirovecii</i> detection in lower respiratory tract samples. [PDF]

Microbiol Spectr
Giardina FAM, Ramus M, Campanini F, Lilleri D, Ferretti V, Pitrolo AMG, Vola A, Maserati R, Baldanti F, Paolucci S.   +9 more
europepmc   +1 more source

Engineered Bacteria Factory Integrating Drug Delivery and Antibody Manufacture for Activating the STING Signal Pathway Mediated Tumor Immunotherapy

Advanced Science, EarlyView.
To address the limitations of protein‐based ICIs in applications, this study constructed an engineered bacterium, HRB, capable of expressing aCD47 in hypoxic TME. Through the Schiff base reaction, responsive liposomes (LC) loaded with the STING agonist cGAMP were connected to the surface of bacteria to form HRB@LC.
Peng‐Shuo Dong, Tian Yao, Yong Li, Zi‐Hui Yan, Xiao‐Ting Xie, Jia‐Hua Zou, Kai Cheng, Jin‐Xuan Fan, Yuan‐Di Zhao, Qiu‐Ran Xu   +9 more
wiley   +1 more source

Selection and evaluation of reference genes for quantitative real-time polymerase chain reaction normalization in Pieris melete (Lepidoptera, Pieridae). [PDF]

J Insect Sci
Jiang T, Liu X, Zou N, Zhang W, Peng Y, Xiao H.   +5 more
europepmc   +1 more source

Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control

Advanced Science, EarlyView.
Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang, Yufeng Xu, Yanfei Hu, Lijun Cao, Ru Jiang, Changtian Chen, Rick Masonbrink, Thomas Maier, Yuchen Tu, Yabo Shi, Enhui Liu, Lingan Kong, Chan Guo, Wei Zhao, Peng Shi, Wenzhen Du, Andrew Severin, Thomas Baum, Deliang Peng, Huan Peng, Mian Zhou, Wei Wang   +21 more
wiley   +1 more source

Rapid intraoperative genetic analysis of adult-type diffuse gliomas using a microfluidic real-time polymerase chain reaction device. [PDF]

Neuro Oncol
Maeda S, Kitano Y, Ohka F, Motomura K, Aoki K, Deguchi S, Shiba Y, Seki M, Ikeda Y, Shimizu H, Iwami K, Takeuchi K, Nagata Y, Yamaguchi J, Kimura K, Takido Y, Yamamoto R, Nakamura A, Ito S, Shinjo K, Kondo Y, Miyagi S, Karube K, Saito R.   +23 more
europepmc   +1 more source

Pooling of porcine fecal samples for quantification of Lawsonia intracellularis by real-time polymerase chain reaction [PDF]

, 2014
Angen, Øystein, Bækbo, Poul, Johansen, Markku, Jorsal, Sven Erik Lind, Nielsen, Jens Peter, Pedersen, Ken Steen   +5 more
core   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Syndromic Testing-The Evaluation of Four Novel Multiplex Real-Time Polymerase Chain Reaction Panels. [PDF]

Diagnostics (Basel)
Yılmaz M, Kilic S, Bayrakdar F, Ötgün SN, Tosun AI, Zeybek U, Çelik F, Aygun G, Safak B, Mahroum N.   +9 more
europepmc   +1 more source

A Dual‐Responsive Versatile Nanohybrid Orchestrating Tumor Elimination and Tumor‐Associated Osteolysis Restoration via Sequential Release

Advanced Science, EarlyView.
The versatile CaO2@CuMOF@HAP nanohybrid demonstrates an outstanding MMP9/pH‐triggered release performance for sequential release of osteogenic growth peptide into deep‐seated tumor‐infiltrated bone destruction areas and dual ions into tumor cells, enabling efficient tumor‐associated osteolysis restoration and tumor elimination for more comprehensive ...
Lan Liu, Han‐Zhe Liu, Zhe‐Nan Liu, Tong Wang, Li‐Li Yu, Qiu‐Jing Li, Zi‐Yi Chen, Guo‐Feng Luo, Zheng‐Jun Shang   +8 more
wiley   +1 more source

Development of a Nano-Real-Time Polymerase Chain Reaction (RT-PCR) Kit for Detection and Genotyping of High-Risk Human Papillomavirus (HPV) Strains Using Dedicated TaqMan Probes. [PDF]

Cureus
Panji M, Modarresi MH, Azizi Z, Absalan M, Motevaseli E.   +4 more
europepmc   +1 more source