Results 221 to 230 of about 731,111 (296)

Comparison of Paired Immunofluorescent Antibody Serology and Real-Time Polymerase Chain Reaction Testing for the Detection of Acute Q Fever among Febrile Patients in Kilimanjaro, Tanzania, 2012-2014. [PDF]

Am J Trop Med Hyg
Rolfe RJ, Crump JA, Maro VP, Mmbaga BT, Saganda W, Lwezaula BF, Couturier MR, Hymas WC, Perniciaro JL, Nicholson WL, Kersh GJ, Rubach MP.   +11 more
europepmc   +1 more source

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

Advanced Science, EarlyView.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou, Xi Zhang, Sihan Chen, Mengchi Yu, Yilan Hu, Chi Gan, Xianghu Meng, Long Li, Ninghong Song   +8 more
wiley   +1 more source

Correction: Tick-Borne Pathogens Screening Using a Multiplex Real-Time Polymerase Chain Reaction-Based Method. [PDF]

Acta Parasitol
Cardenas-Cadena SA, Castañeda-Lopez ME, Mollinedo-Montaño FE, Vazquez-Reyes S, Lara-Arias J, Marino-Martinez IA, Rodriguez-Sanchez IP, Garza-Veloz I, Martinez-Fierro ML.   +8 more
europepmc   +1 more source

Multimodal Multiorgan‐on‐a‐Chip Platform for Probing Liver‐Tumor Interactions and Advancing Prodrug Screening

Advanced Science, EarlyView.
This work introduces a multimodal multi‐OoC platform that overcomes current limitations in liver‐tumor interaction studies and prodrug screening. By integrating dynamic microfluidic circuits, electrochemical sensing, and mass analysis, this platform enables non‐invasive, longitudinal monitoring of drug metabolism and hepatotoxicity, offering a ...
Dan Wang, Yisong Huang, Weijian Zhao, Tian Chen, Siyu Bai, Denghui Guo, Mengying Wang, Yaoyao Zhao, Liang Zhao, Guangsheng Guo, Xiayan Wang   +10 more
wiley   +1 more source

The employment of real-time polymerase chain reaction for analysis of canine meat in meatball products for halal authentication analysis. [PDF]

J Adv Vet Anim Res
Rumiyati R, Arini RL, Purwanto P, Rohman A.   +3 more
europepmc   +1 more source

Injectable Porous Microspheres Loaded With Biomimetic Preconditioned Bone Marrow Mesenchymal Stem Cell‐Derived Exosomes for Vascularized Bone Regeneration

Advanced Science, EarlyView.
Schematic illustration of injectable PDA‐modified GelMA microspheres loaded with BioPre‐Exos for vascularized bone regeneration. ABSTRACT Critical‐sized bone defects remain a highly challenging clinical problem due to insufficient intrinsic self‐healing capacity.
Lijun Li, Hao Zhang, Lingtong Sun, Yingfeng Su, Yang Xu, Jian Huang, Jingchao Wen, Jinjin Zhu, Jianjun Ma, Wenbin Xu   +9 more
wiley   +1 more source

Comparative evaluation of real-time polymerase chain reaction, conventional PCR and microscopy for detection of <i>Babesia bigemina</i> in bovines of Punjab (India). [PDF]

J Parasit Dis
Kaur P, Juyal PD, Sharma A, Chachra D, Mukhopadhyay CS, Singla LD.   +5 more
europepmc   +1 more source

Self‐Amplifying Redox Cycle Triggers Ferroptosis/Cuproptosis Synergy for Enhanced Bacterial Eradication

Advanced Science, EarlyView.
This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao, Shaolong Qiu, Jiangli Cao, Jifeng Liu, Zhiyong Song, Ting Du, Xinjun Du   +6 more
wiley   +1 more source

SETD1A Regulates Glycolysis and Senescence of Nucleus Pulposus Cells via H3K4me3–HELZ2/PPARα‐HIF1α Axis to Drive Intervertebral Disc Degeneration

Advanced Science, EarlyView.
SETD1A is a key epigenetic regulator in NPCs during IDD. In normal NPCs, it sustains H3K4me3–HELZ2/PPARα–HIF1α signaling to maintain glycolytic energy metabolism and proliferation. In degenerated NPCs, reduced SETD1A disrupts this axis, impairing glycolysis and accelerating senescence, highlighting a promising therapeutic target for IDD.
Jiawei Fu, Xue Leng, Jiang Long, Zhengao Liao, Xiaoqin An, Xuezheng Ai, Dan Long, Changqing Li, Bo Huang, Yue Zhou, Shiwu Dong, Chencheng Feng   +11 more
wiley   +1 more source

Macroepidemiological trends of Influenza A virus detection through reverse transcription real-time polymerase chain reaction (RT-rtPCR) in porcine samples in the United States over the last 20 years. [PDF]

Front Vet Sci
Moraes DCA, Cezar GA, Magalhães ES, Nicolino RR, Rupasinghe K, Chandra S, Silva GS, Almeida MN, Crim B, Burrough ER, Gauger PC, Madson D, Thomas J, Zeller MA, Main R, Thurn M, Lages P, Corzo CA, Sturos M, Naikare H, McGaughey R, Matias Ferreyra F, Retallick J, Gebhardt J, McReynolds S, Greseth J, Kersey D, Clement T, Pillatzki A, Christopher-Hennings J, Thompson BS, Prarat M, Summers D, Bowen C, Boyle J, Hendrix K, Lyons J, Werling K, Arruda AG, Schwartz M, Yeske P, Murray D, Mason B, Schneider P, Copeland S, Dufresne L, Boykin D, Fruge C, Hollis W, Robbins RC, Petznick T, Kuecker K, Glowzenski L, Niederwerder M, Linhares DCL, Trevisan G.   +55 more
europepmc   +1 more source